[HTML][HTML] CC chemokines in a tumor: a review of pro-cancer and anti-cancer properties of the ligands of receptors CCR1, CCR2, CCR3, and CCR4
J Korbecki, K Kojder, D Simińska… - International journal of …, 2020 - mdpi.com
CC chemokines, a subfamily of 27 chemotactic cytokines, are a component of intercellular
communication, which is crucial for the functioning of the tumor microenvironment. Although …
communication, which is crucial for the functioning of the tumor microenvironment. Although …
[HTML][HTML] Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
Esophageal cancer (EC) is a disease often marked by aggressive growth and poor
prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant …
prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant …
CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling
X Zhang, L Chen, W Dang, M Cao, J Xiao, S Lv… - Laboratory …, 2020 - nature.com
Tumor-associated macrophages (TAMs) constitute a large population of glioblastoma and
facilitate tumor growth and invasion of tumor cells, but the underlying mechanism remains …
facilitate tumor growth and invasion of tumor cells, but the underlying mechanism remains …
[HTML][HTML] Hypoxia-induced ZEB1 promotes cervical cancer progression via CCL8-dependent tumour-associated macrophage recruitment
XJ Chen, YR Deng, ZC Wang, WF Wei, CF Zhou… - Cell Death & …, 2019 - nature.com
The accumulation of tumour-associated macrophages (TAMs) in the hypoxic tumour
microenvironment (TME) is associated with malignant progression in cancer. However, the …
microenvironment (TME) is associated with malignant progression in cancer. However, the …
Bronchial epithelial cell extracellular vesicles ameliorate epithelial–mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization
S He, D Chen, M Hu, L Zhang, C Liu, D Traini… - … , Biology and Medicine, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is partly characterized as epithelial–
mesenchymal transition (EMT)-related airflow limitation. Extracellular vesicles (EVs) play …
mesenchymal transition (EMT)-related airflow limitation. Extracellular vesicles (EVs) play …
[HTML][HTML] Resolution of deep venous thrombosis: proposed immune paradigms
JM Nicklas, AE Gordon, PK Henke - International Journal of Molecular …, 2020 - mdpi.com
Venous thromboembolism (VTE) is a pathology encompassing deep vein thrombosis (DVT)
and pulmonary embolism (PE) associated with high morbidity and mortality. Because …
and pulmonary embolism (PE) associated with high morbidity and mortality. Because …
[HTML][HTML] Correlation of CCL8 expression with immune cell infiltration of skin cutaneous melanoma: potential as a prognostic indicator and therapeutic pathway
P Yang, W Chen, H Xu, J Yang, J Jiang, Y Jiang… - Cancer Cell …, 2021 - Springer
Background The tumor microenvironment (TME) is critical in the progression and metastasis
of skin cutaneous melanoma (SKCM). Differences in tumor-infiltrating immune cells (TICs) …
of skin cutaneous melanoma (SKCM). Differences in tumor-infiltrating immune cells (TICs) …
[HTML][HTML] MiR-345-5p functions as a tumor suppressor in pancreatic cancer by directly targeting CCL8
T Mou, F Xie, P Zhong, H Hua, L Lai, Q Yang… - Biomedicine & …, 2019 - Elsevier
Background Increasing evidence has demonstrated that microRNAs (miRNAs) are key
regulators of human diseases and can serve as prognostic markers for several cancers …
regulators of human diseases and can serve as prognostic markers for several cancers …
CXCL6 fuels the growth and metastases of esophageal squamous cell carcinoma cells both in vitro and in vivo through upregulation of PD‐L1 via activation of STAT3 …
S Zheng, T Shen, Q Liu, T Liu, A Tuerxun… - Journal of Cellular …, 2021 - Wiley Online Library
Abstract CXCL6, contraction of C‐X‐C motif chemokine ligand 6, whose biological roles
have been rarely described in esophageal squamous cell carcinoma (ESCC). To …
have been rarely described in esophageal squamous cell carcinoma (ESCC). To …
CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity
ES Kim, SM Nam, HK Song, S Lee, K Kim, HK Lim… - Oncogene, 2021 - nature.com
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a poor
prognosis for which no effective therapeutic measures are currently available. The present …
prognosis for which no effective therapeutic measures are currently available. The present …