Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection

M Castanheira, PJ Simner… - JAC-antimicrobial …, 2021 - academic.oup.com
Extended-spectrum β-lactamase (ESBL)-producing Gram-negative pathogens are a major
cause of resistance to expanded-spectrum β-lactam antibiotics. Since their discovery in the …

[HTML][HTML] Blood culture-based diagnosis of bacteraemia: state of the art

O Opota, A Croxatto, G Prod'Hom, G Greub - Clinical Microbiology and …, 2015 - Elsevier
Blood culture remains the best approach to identify the incriminating microorganisms when
a bloodstream infection is suspected, and to guarantee that the antimicrobial treatment is …

Intercontinental spread of OXA-48 beta-lactamase-producing Enterobacteriaceae over a 11-year period, 2001 to 2011

A Potron, L Poirel, E Rondinaud… - …, 2013 - eurosurveillance.org
OXA-48 beta-lactamase producers are emerging as an important threat mostly in the
Mediterranean area. We report here the molecular epidemiology of a collection of OXA-48 …

β-lactam and β-lactamase inhibitor combinations in the treatment of extended-spectrum β-lactamase producing Enterobacteriaceae: time for a reappraisal in the era of …

PNA Harris, PA Tambyah, DL Paterson - The Lancet Infectious …, 2015 - thelancet.com
The spread of extended-spectrum β-lactamase (ESBL) genes in Enterobacteriaceae such as
Escherichia coli or Klebsiella spp is a major challenge to modern medical practice …

Detection of Multidrug-Resistant Enterobacterales—From ESBLs to Carbapenemases

J Noster, P Thelen, A Hamprecht - Antibiotics, 2021 - mdpi.com
Multidrug-resistant Enterobacterales (MDRE) are an emerging threat to global health,
leading to rising health care costs, morbidity and mortality. Multidrug-resistance is commonly …

Modified CLSI extended-spectrum β-lactamase (ESBL) confirmatory test for phenotypic detection of ESBLs among Enterobacteriaceae producing various β …

A Poulou, E Grivakou, G Vrioni, V Koumaki… - Journal of clinical …, 2014 - Am Soc Microbiol
The worldwide dissemination of Enterobacteriaceae producing AmpC β-lactamases and
carbapenemases makes difficult the phenotypic detection of extended-spectrum β …

Emerging microtechnologies and automated systems for rapid bacterial identification and antibiotic susceptibility testing

Y Li, X Yang, W Zhao - SLAS TECHNOLOGY: Translating …, 2017 - journals.sagepub.com
Rapid bacterial identification (ID) and antibiotic susceptibility testing (AST) are in great
demand due to the rise of drug-resistant bacteria. Conventional culture-based AST methods …

Validation of carbapenemase and extended-spectrum β-lactamase multiplex endpoint PCR assays according to ISO 15189

P Bogaerts, R Rezende de Castro… - Journal of …, 2013 - academic.oup.com
Objectives To validate and accredit a set of three multiplex endpoint PCR assays, targeting
the most important carbapenemase and minor extended-spectrum β-lactamase (ESBL) …

[HTML][HTML] High rate of faecal carriage of extended-spectrum β-lactamase and OXA-48 carbapenemase-producing Enterobacteriaceae at a university hospital in …

D Girlich, N Bouihat, L Poirel, A Benouda… - Clinical Microbiology …, 2014 - Elsevier
Carbapenemase-producing Enterobacteriaceae isolates are being increasingly reported,
particularly from countries surrounding the Mediterranean area. We aimed to quantify the …

Occurrence of CTX-M-15-and MCR-1-producing Enterobacterales in pigs in Portugal: Evidence of direct links with antibiotic selective pressure

C Fournier, M Aires-de-Sousa, P Nordmann… - International journal of …, 2020 - Elsevier
Aims To undertake a prospective analysis of the occurrence of colistin-resistant and
extended-spectrum ß-lactamase (ESBL)-producing Enterobacterales colonizing pigs at two …