[HTML][HTML] Bioinspired mineralized collagen scaffolds for bone tissue engineering

Z Li, T Du, C Ruan, X Niu - Bioactive materials, 2021 - Elsevier
Successful regeneration of large segmental bone defects remains a major challenge in
clinical orthopedics, thus it is of important significance to fabricate a suitable alternative …

Fabrication, applications and challenges of natural biomaterials in tissue engineering

S Ullah, X Chen - Applied Materials Today, 2020 - Elsevier
Natural biomaterials are extensively used in tissue engineering due to their microstructure
interconnectivity and inherent bioactivity which mimics of natural extracellular matrix (ECM) …

Fabrication and mechanical characterization of 3D printed vertical uniform and gradient scaffolds for bone and osteochondral tissue engineering

SM Bittner, BT Smith, L Diaz-Gomez, CD Hudgins… - Acta biomaterialia, 2019 - Elsevier
Recent developments in 3D printing (3DP) research have led to a variety of scaffold designs
and techniques for osteochondral tissue engineering; however, the simultaneous …

Collagen scaffolds functionalised with copper-eluting bioactive glass reduce infection and enhance osteogenesis and angiogenesis both in vitro and in vivo

EJ Ryan, AJ Ryan, A González-Vázquez, A Philippart… - Biomaterials, 2019 - Elsevier
The bone infection osteomyelitis (typically by Staphylococcus aureus) usually requires a
multistep procedure of surgical debridement, long-term systemic high-dose antibiotics, and …

A strong, tough, and osteoconductive hydroxyapatite mineralized polyacrylamide/dextran hydrogel for bone tissue regeneration

J Fang, P Li, X Lu, L Fang, X Lü, F Ren - Acta biomaterialia, 2019 - Elsevier
The design of hydrogels with adequate mechanical properties and excellent bioactivity,
osteoconductivity, and capacity for osseointegration is essential to bone repair and …

Bone biomaterials for overcoming antimicrobial resistance: Advances in non-antibiotic antimicrobial approaches for regeneration of infected osseous tissue

JM Sadowska, KJ Genoud, DJ Kelly, FJ O'Brien - Materials Today, 2021 - Elsevier
Eliminating bacterial infection and simultaneously providing a bioactive environment for
bone growth during treatment of severe osteomyelitis is one of the greatest global …

[HTML][HTML] Recent development in multizonal scaffolds for osteochondral regeneration

L Yu, S Cavelier, B Hannon, M Wei - Bioactive Materials, 2023 - Elsevier
Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues

T Gonzalez-Fernandez, S Rathan, C Hobbs… - Journal of Controlled …, 2019 - Elsevier
The regeneration of complex tissues and organs remains a major clinical challenge. With a
view towards bioprinting such tissues, we developed a new class of pore-forming bioink to …

[HTML][HTML] Dual scaffold delivery of miR-210 mimic and miR-16 inhibitor enhances angiogenesis and osteogenesis to accelerate bone healing

IM Castaño, RM Raftery, G Chen, B Cavanagh… - Acta Biomaterialia, 2023 - Elsevier
Angiogenesis is critical for successful bone repair, and interestingly, miR-210 and miR-16
possess counter-active targets involved in both angiogenesis and osteogenesis: miR-210 …

A multifunctional scaffold for bone infection treatment by delivery of microRNA therapeutics combined with antimicrobial nanoparticles

JM Sadowska, RN Power, KJ Genoud… - Advanced …, 2024 - Wiley Online Library
Treating bone infections and ensuring bone repair is one of the greatest global challenges
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …