This narrative review aims to pinpoint mental and behavioral effects of starvation, which may
be triggered by hypoleptinemia and as such may be amenable to treatment with leptin …

Dysfunctional signaling in midbrain reward circuits perpetuates diseases characterized by
compulsive overconsumption of rewarding substances such as substance abuse, binge …

Understanding the neurobiological controls of feeding behavior is critical in light of the
growing obesity pandemic, a phenomenon largely based on excessive caloric consumption …

Overconsumption of high caloric food plays an important role in the etiology of obesity.
Several factors drive such hedonic feeding. High caloric food is often palatable. In addition …

The endocannabinoid system (ECS) is a widespread intercellular signaling system that
plays a critical role in energy homeostasis, meant as the precise matching of caloric intake …

The adipose hormone leptin potently influences physical activity. Leptin can decrease
locomotion and running, yet the mechanisms involved and the influence of leptin on the …

Polypeptides produced in the gastrointestinal tract, stomach, adipocytes, pancreas and brain
that influence food intake are referred to as 'feeding-related'peptides. Most peptides that …

The growing worldwide prevalence of overnutrition and underexertion threatens the gains
that we have made against atherosclerotic cardiovascular disease and other maladies …

Increasing evidence suggests that obesity and aberrant proliferation of nucleus pulposus
(NP) cells are associated with intervertebral disc degeneration. Leptin, a hormone with …

Understanding the neurobiological substrates that encode learning about food‐associated
cues and how those signals are modulated is of great clinical importance especially in light …