Abstract Scope In 2009, the European Society of Clinical Microbiology and Infectious
Diseases (ESCMID) published the first treatment guidance document for Clostridioides …

Objectives Clostridioides difficile infection (CDI), its subsequent recurrences (rCDIs), and
severe CDI (sCDI) provide a significant burden for both patients and the healthcare system …

Introduction: Clostridium difficile infection (CDI) has become a significant healthcare-
associated infection and is strongly associated with antibiotic use. Practice guidelines have …

Background Clostridioides difficile infection (CDI) is the most common hospital acquired
infection in the USA, with recurrence rates> 15%. Although primary CDI has been …

Abstract Background Clostridium (Clostridioides) difficile infection (CDI) is a health care–
associated infection that can lead to serious complications. Potential complications include …

Introduction Clostridioides difficile infection (CDI) is the main cause of nosocomial diarrhoea
in developed countries. Recurrent CDI (R-CDI), which affects 20%-30% of patients and …

Abstract Background Recurrent Clostridioides difficile infection (CDI) is a major public health
threat. While clinical prediction tools exist, they do not incorporate the newest Infectious …

Background Clostridioides difficile infection results in life-threatening short-term outcomes
and the potential for subsequent recurrent infection. Predicting these outcomes at diagnosis …

This document gathers the opinion of a multidisciplinary forum of experts on different
aspects of the diagnosis and treatment of Clostridioides difficile infection (CDI) in Spain. It …

Background Endogenous antibodies (eAbs) against Clostridioides (Clostridium) difficile
toxins may protect against recurrence of C. difficile infection (rCDI). This hypothesis was …