Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

Growth of oral bacteria in situ requires adhesion to a surface because the constant flow of
host secretions thwarts the ability of planktonic cells to grow before they are swallowed …

Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

Studies from the 1960s indicated that increased microbial diversity and a succession in the
predominant bacterial species in plaque correlate with the appearance of gingival …

dihydroxy‐2, 3‐pentanedione (DPD), a product of the LuxS enzyme in the catabolism of S‐
ribosylhomocysteine, spontaneously cyclizes to form autoinducer 2 (AI‐2). AI‐2 is proposed …

Host-microbial symbioses are vital to health; nonetheless, little is known about the role
crosskingdom signaling plays in these relationships. In a process called quorum sensing …

Bacteria sense their environment using receptors of the histidine sensor kinase family, but
how kinase activity is regulated by ligand binding is not well understood. Autoinducer-2 (AI …

Bacteria can regulate community‐wide behaviors including biofilm formation, virulence,
conjugation, sporulation, and swarming motility through a process called quorum sensing …

Vibrio cholerae possesses multiple quorum-sensing (QS) systems that control virulence and
biofilm formation among other traits. At low cell densities, when QS autoinducers are absent …

ABSTRACT Autoinducer 2 (AI-2) is widely recognized as a signal molecule for intra-and
interspecies communication in Gram-negative bacteria, but its signaling function in Gram …