α1-adrenoceptor activity of β-adrenoceptor ligands–An expected drug property with limited clinical relevance

MC Michel - European Journal of Pharmacology, 2020 - Elsevier
Many β-adrenoceptor agonists and antagonists including several clinically used drugs have
been reported to also exhibit binding to α 1-adrenoceptors. Such promiscuity within the …

Novel prognostication biomarker adipophilin reveals a metabolic shift in uveal melanoma and new therapeutic opportunities

M Matareed, E Maranou, SA Koskela… - The Journal of …, 2023 - Wiley Online Library
Metastatic uveal melanoma remains incurable at present. We previously demonstrated that
loss of BAP1 gene expression in tumour cells triggers molecular mechanisms of …

Electrospun nanofibers modified with zeolitic imidazolate framework-8 for electrochemiluminescent determination of terbutaline

Z Sun, J Lu, X Zhang, X Shan, Q Wu, Y Zhao, L Tian - Microchimica Acta, 2022 - Springer
For the first time it is demonstrated that zeolitic imidazolate framework-8 electrospun
nanofibers (ZIF-8 NF) could serve as electrochemiluminescence (ECL) accelerator for the …

[PDF][PDF] Effect of methoxymine on prevention and treatment of myocardial injury and cardiac function in elderly patients with hypotension during intraspinal anesthesia.

JG Ren, B Cai, H Wang, XL Wang… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: We aimed to investigate the effects of methoxamine to prevent hypotension in
the elderly with intraspinal anesthesia (IA) on myocardial injury and cardiac function …