Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

Several lines of evidence suggest that brain function and behaviour are influenced by
microbial metabolites. Key products of the microbiota are short-chain fatty acids (SCFAs) …

As interest in the gut microbiome has grown in recent years, attention has turned to the
impact of our diet on our brain. The benefits of a high fiber diet in the colon have been well …

Mechanisms of epigenetic regulation, including DNA methylation, chromatin remodeling,
and histone post-translational modifications, are involved in multiple aspects of neuronal …

Neurodegenerative diseases are a group of pathological conditions that cause motor inc-
ordination (jerking movements), cognitive and memory impairments result from …

Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …

Long-lasting memories require specific gene expression programmes that are, in part,
orchestrated by epigenetic mechanisms. Of the epigenetic modifications identified in …

Huntington's disease is an autosomal-dominant, progressive neurodegenerative disorder
with a distinct phenotype, including chorea and dystonia, incoordination, cognitive decline …

Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat
expansion in the gene encoding for huntingtin protein. A lot has been learned about this …

The discovery that expansion of unstable repeats can cause a variety of neurological
disorders has changed the landscape of disease-oriented research for several forms of …