Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics
Y Duan, K Gong, S Xu, F Zhang, X Meng… - Signal Transduction and …, 2022 - nature.com
Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …
[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease
A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …
several types of adipose tissue have been identified, namely white, brown, and beige, that …
[HTML][HTML] Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases
L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …
and complex endocrine organ, which produces and secretes several adipokines, including …
Antioxidant and anti-inflammatory potential of polyphenols contained in mediterranean diet in obesity: Molecular mechanisms
Nutrition transition can be defined as shifts in food habits, and it is characterized by high-fat
(chiefly saturated animal fat), hypercaloric and salty food consumption at the expense of …
(chiefly saturated animal fat), hypercaloric and salty food consumption at the expense of …
The evolving view of thermogenic adipocytes—ontogeny, niche and function
The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …
reached pandemic levels. Central to the development of these metabolic disorders is …
Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice
Objective To investigate the abundance and the prevalence of Dysosmobacter welbionis
J115T, a novel butyrate-producing bacterium isolated from the human gut both in the …
J115T, a novel butyrate-producing bacterium isolated from the human gut both in the …
Sarcopenia: etiology, nutritional approaches, and miRNAs
Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically
affects the quality of life. Although there is a consensus that sarcopenia is a multifactorial …
affects the quality of life. Although there is a consensus that sarcopenia is a multifactorial …
The endocrine role of brown adipose tissue: An update on actors and actions
In recent years, brown adipose tissue (BAT) has been recognized not only as a main site of
non-shivering thermogenesis in mammals, but also as an endocrine organ. BAT secretes a …
non-shivering thermogenesis in mammals, but also as an endocrine organ. BAT secretes a …
Brown and beige adipose tissue and aging
E Zoico, S Rubele, A De Caro, N Nori… - Frontiers in …, 2019 - frontiersin.org
Across aging, adipose tissue (AT) changes its quantity and distribution: AT becomes
dysfunctional with an increase in production of inflammatory peptides, a decline of those …
dysfunctional with an increase in production of inflammatory peptides, a decline of those …
Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation
Inflammation is an adaptive response of the immune system to tissue malfunction or
homeostatic imbalance. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) …
homeostatic imbalance. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) …