The fetus and newborn face a complex set of immunological demands, including protection
against infection, avoidance of harmful inflammatory immune responses that can lead to pre …

Diagnostic markers of infection are useful indicators of neonatal sepsis. Serial
measurements of infection markers can improve diagnostic sensitivity, and the use of …

The human neonate and infant are unduly susceptible to infection with a wide variety of
microbes. This susceptibility is thought to reflect differences from adults in innate and …

Neonates, particularly those born prematurely, are among the most vulnerable age group for
morbidity and mortality due to infections. Immaturity of the innate immune system and a high …

Accurate and timely diagnosis of early onset neonatal sepsis remains challenging to the
clinician and the laboratory. A test with a rapid turnaround time with 100% sensitivity, rather …

Host defenses to microbial invasion include the phylogenetically older but rapidly
developing antigen-independent or innate immunity and the much more slowly developing …

Human newborns are susceptible to microbial infection related to incompletely defined
aspects of the neonatal immune system. To characterize neonatal innate immunity, we …

BACKGROUND: Vitamin C (ascorbic acid) is an essential water-soluble nutrient which
primarily exerts its effect on immune homeostasis as physiological antioxidant. However …

Reactive oxygen species play an important role in the pathogenesis of respiratory distress
syndrome and its complications. This study was conducted to determine if treatment with the …

The inflammatory response plays a major role in the induction of several neonatal diseases.
We hypothesize that an imbalance between the pro-and anti-inflammatory response is …