Chronic stress, drug use, and vulnerability to addiction

R Sinha - Annals of the new York Academy of Sciences, 2008 - Wiley Online Library
Stress is a well‐known risk factor in the development of addiction and in addiction relapse
vulnerability. A series of population‐based and epidemiological studies have identified …

[HTML][HTML] Dopamine, serotonin and impulsivity

JW Dalley, JP Roiser - Neuroscience, 2012 - Elsevier
Impulsive people have a strong urge to act without thinking. It is sometimes regarded as a
positive trait but rash impulsiveness is also widely present in clinical disorders such as …

Rejecting impulsivity as a psychological construct: A theoretical, empirical, and sociocultural argument.

JC Strickland, MW Johnson - Psychological review, 2021 - psycnet.apa.org
We demonstrate through theoretical, empirical, and sociocultural evidence that the concept
of impulsivity fails the basic requirements of a psychological construct and should be …

Sex differences in the neural mechanisms mediating addiction: a new synthesis and hypothesis

JB Becker, AN Perry, C Westenbroek - Biology of sex differences, 2012 - Springer
In this review we propose that there are sex differences in how men and women enter onto
the path that can lead to addiction. Males are more likely than females to engage in risky …

Genetic variation in components of dopamine neurotransmission impacts ventral striatal reactivity associated with impulsivity

EE Forbes, SM Brown, M Kimak, RE Ferrell… - Molecular …, 2009 - nature.com
Individual differences in traits such as impulsivity involve high reward sensitivity and are
associated with risk for substance use disorders. The ventral striatum (VS) has been widely …

Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence

MN Potenza, KA Hong, CM Lacadie… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: Although stress and drug cue exposure each increase drug craving and
contribute to relapse in cocaine dependence, no previous research has directly examined …

Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity

P Trifilieff, D Martinez - Neuropharmacology, 2014 - Elsevier
Dependence to drugs of abuse is closely associated with impulsivity, or the propensity to
choose a lower, but immediate, reward over a delayed, but more valuable outcome. Here …

Stress, alcohol and drug interaction: an update of human research

M Uhart, GS Wand - Addiction biology, 2009 - Wiley Online Library
ABSTRACT A challenging question that continues unanswered in the field of addiction is
why some individuals are more vulnerable to substance use disorders than others …

[HTML][HTML] Individual differences in the proneness to have flow experiences are linked to dopamine D2-receptor availability in the dorsal striatum

Ö De Manzano, S Cervenka, A Jucaite, O Hellenäs… - NeuroImage, 2013 - Elsevier
Flow is a subjective experience of high but effortless attention, enjoyment, and low self-
awareness that can occur during the active performance of challenging tasks. The …

[HTML][HTML] Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder

D Denys, F de Vries, D Cath, M Figee, N Vulink… - European …, 2013 - Elsevier
Tourette syndrome (TS) and obsessive-compulsive disorder (OCD) both are
neuropsychiatric disorders associated with abnormalities in dopamine neurotransmission …