Risk of fracture with thiazolidinediones: an updated meta-analysis of randomized clinical trials
ZN Zhu, YF Jiang, T Ding - Bone, 2014 - Elsevier
Objective The use of thiazolidinediones (TZDs) has been associated with increased fracture
risk. We performed a comprehensive literature review and meta-analysis to estimate the risk …
risk. We performed a comprehensive literature review and meta-analysis to estimate the risk …
Recent advances in pharmacotherapy for hypertriglyceridemia
A Sahebkar, GT Chew, GF Watts - Progress in lipid research, 2014 - Elsevier
Elevated plasma triglyceride (TG) concentrations are associated with an increased risk of
atherosclerotic cardiovascular disease (CVD), hepatic steatosis and pancreatitis. Existing …
atherosclerotic cardiovascular disease (CVD), hepatic steatosis and pancreatitis. Existing …
Pioglitazone use and risk of bladder cancer and other common cancers in persons with diabetes
JD Lewis, LA Habel, CP Quesenberry, BL Strom… - Jama, 2015 - jamanetwork.com
Importance Studies suggest pioglitazone use may increase risk of cancers. Objective To
examine whether pioglitazone use for diabetes is associated with risk of bladder and 10 …
examine whether pioglitazone use for diabetes is associated with risk of bladder and 10 …
Thiazolidinediones and associated risk of bladder cancer: a systematic review and meta‐analysis
RM Turner, CS Kwok, C Chen‐Turner… - British journal of …, 2014 - Wiley Online Library
Aims To determine whether thiazolidinedione use is associated with a risk of bladder
cancer. Methods We searched MEDLINE and EMBASE in J une 2012 (with P ub M ed …
cancer. Methods We searched MEDLINE and EMBASE in J une 2012 (with P ub M ed …
Metformin and metabolic diseases: a focus on hepatic aspects
Metformin has been widely used as a first-line anti-diabetic medicine for the treatment of
type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses …
type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses …
Pleiotropic effects of type 2 diabetes management strategies on renal risk factors
MHA Muskiet, L Tonneijck, MM Smits… - The Lancet Diabetes & …, 2015 - thelancet.com
In parallel with the type 2 diabetes pandemic, diabetic kidney disease has become the
leading cause of end-stage renal disease worldwide, and is associated with high …
leading cause of end-stage renal disease worldwide, and is associated with high …
Assessing the need for pioglitazone in the treatment of patients with type 2 diabetes: a meta-analysis of its risks and benefits from prospective trials
B Sinha, S Ghosal - Scientific Reports, 2020 - nature.com
The safety and usefulness of pioglitazone (Pio) is repeatedly called into question due to the
contradictory information available about it. A meta-analysis and risk benefit assessment …
contradictory information available about it. A meta-analysis and risk benefit assessment …
Gastro-floating bilayer tablets for the sustained release of metformin and immediate release of pioglitazone: Preparation and in vitro/in vivo evaluation
W He, Y Li, R Zhang, Z Wu, L Yin - International journal of pharmaceutics, 2014 - Elsevier
Owing to the complementary mechanisms of action of metformin hydrochloride (MH) and
pioglitazone hydrochloride (PG), combination therapy for type 2 diabetes mellitus using the …
pioglitazone hydrochloride (PG), combination therapy for type 2 diabetes mellitus using the …
Effective therapeutic delivery and bioavailability enhancement of pioglitazone using drug in adhesive transdermal patch
The administration of pioglitazone as an oral therapy is restricted due to various challenges.
The aim of the current investigation was to evaluate the suitability of pioglitazone in …
The aim of the current investigation was to evaluate the suitability of pioglitazone in …
A review on thiazolidinediones and bladder cancer in human studies
CH Tseng - Journal of Environmental Science and Health, Part C, 2014 - Taylor & Francis
There is a concern of an increased risk of bladder cancer associated with the use of
thiazolidinediones, a class of oral glucose-lowering drugs commonly used in patients with …
thiazolidinediones, a class of oral glucose-lowering drugs commonly used in patients with …