In Vivo Organic Bioelectronics for Neuromodulation

M Berggren, ED Głowacki, DT Simon… - Chemical …, 2022 - ACS Publications
The nervous system poses a grand challenge for integration with modern electronics and
the subsequent advances in neurobiology, neuroprosthetics, and therapy which would …

Optogenetics: 10 years of microbial opsins in neuroscience

K Deisseroth - Nature neuroscience, 2015 - nature.com
Over the past 10 years, the development and convergence of microbial opsin engineering,
modular genetic methods for cell-type targeting and optical strategies for guiding light …

Tether-free photothermal deep-brain stimulation in freely behaving mice via wide-field illumination in the near-infrared-II window

X Wu, Y Jiang, NJ Rommelfanger, F Yang… - Nature Biomedical …, 2022 - nature.com
Neural circuitry is typically modulated via invasive brain implants and tethered optical fibres
in restrained animals. Here we show that wide-field illumination in the second near-infrared …

Neural recording and modulation technologies

R Chen, A Canales, P Anikeeva - Nature Reviews Materials, 2017 - nature.com
In the mammalian nervous system, billions of neurons connected by quadrillions of
synapses exchange electrical, chemical and mechanical signals. Disruptions to this network …

Next-generation probes, particles, and proteins for neural interfacing

J Rivnay, H Wang, L Fenno, K Deisseroth… - Science …, 2017 - science.org
Bidirectional interfacing with the nervous system enables neuroscience research, diagnosis,
and therapy. This two-way communication allows us to monitor the state of the brain and its …

Subretinally injected semiconducting polymer nanoparticles rescue vision in a rat model of retinal dystrophy

JF Maya-Vetencourt, G Manfredi, M Mete… - Nature …, 2020 - nature.com
Inherited retinal dystrophies and late-stage age-related macular degeneration, for which
treatments remain limited, are among the most prevalent causes of legal blindness. Retinal …

Gold nanostructures: synthesis, properties, and neurological applications

I Zare, MT Yaraki, G Speranza, AH Najafabadi… - Chemical society …, 2022 - pubs.rsc.org
Recent advances in technology are expected to increase our current understanding of
neuroscience. Nanotechnology and nanomaterials can alter and control neural functionality …

Nanotransducer-enabled deep-brain neuromodulation with NIR-II light

X Wu, F Yang, S Cai, K Pu, G Hong - ACS nano, 2023 - ACS Publications
The second near-infrared window (NIR-II window), which ranges from 1000 to 1700 nm in
wavelength, exhibits distinctive advantages of reduced light scattering and thus deep …

Bioresorbable thin-film silicon diodes for the optoelectronic excitation and inhibition of neural activities

Y Huang, Y Cui, H Deng, J Wang, R Hong… - Nature Biomedical …, 2023 - nature.com
Neural activities can be modulated by leveraging light-responsive nanomaterials as
interfaces for exerting photothermal, photoelectrochemical or photocapacitive effects on …

Reversible photothermal modulation of electrical activity of excitable cells using polydopamine nanoparticles

H Gholami Derami, P Gupta, KC Weng… - Advanced …, 2021 - Wiley Online Library
Advances in the design and synthesis of nanomaterials with desired biophysicochemical
properties can be harnessed to develop non‐invasive neuromodulation technologies. Here …