Annual research review: Early adversity, the hypothalamic–pituitary–adrenocortical axis, and child psychopathology
Background Research on early adversity, stress biology, and child development has grown
exponentially in recent years. Findings We review the current evidence for the hypothalamic …
exponentially in recent years. Findings We review the current evidence for the hypothalamic …
Gestational factors throughout fetal neurodevelopment: the serotonin link
SI Hanswijk, M Spoelder, L Shan, MMM Verheij… - International journal of …, 2020 - mdpi.com
Serotonin (5-HT) is a critical player in brain development and neuropsychiatric disorders.
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …
The HPA axis during the perinatal period: implications for perinatal depression
MJ Dickens, JL Pawluski - Endocrinology, 2018 - academic.oup.com
The transition to motherhood is characterized by some of the most pronounced endocrine
changes a woman will experience in her lifetime. Unfortunately, matrescence is also a time …
changes a woman will experience in her lifetime. Unfortunately, matrescence is also a time …
Prenatal influences on temperament development: The role of environmental epigenetics
MA Gartstein, MK Skinner - Development and Psychopathology, 2018 - cambridge.org
This review summarizes current knowledge and outlines future directions relevant to
questions concerning environmental epigenetics and the processes that contribute to …
questions concerning environmental epigenetics and the processes that contribute to …
Of rodents and humans: A comparative review of the neurobehavioral effects of early life SSRI exposure in preclinical and clinical research
ME Glover, SM Clinton - International Journal of Developmental …, 2016 - Elsevier
Selective serotonin reuptake inhibitors (SSRIs) have been a mainstay pharmacological
treatment for women experiencing depression during pregnancy and postpartum for the past …
treatment for women experiencing depression during pregnancy and postpartum for the past …
Fluoxetine normalizes the effects of prenatal maternal stress on depression-and anxiety-like behaviors in mouse dams and male offspring
AA Salari, L Fatehi-Gharehlar, N Motayagheni… - Behavioural brain …, 2016 - Elsevier
Maternal depression during pregnancy and the postpartum period (lactation) is a common
debilitating condition affecting mother-fetus/-infant interactions, which can be a risk factor for …
debilitating condition affecting mother-fetus/-infant interactions, which can be a risk factor for …
The effects of maternal depression and maternal selective serotonin reuptake inhibitor exposure on offspring
JDA Olivier, H Åkerud, H Kaihola… - Frontiers in cellular …, 2013 - frontiersin.org
It has been estimated that 20% of pregnant women suffer from depression and it is well-
documented that maternal depression can have long-lasting effects on the child. Currently …
documented that maternal depression can have long-lasting effects on the child. Currently …
Perinatal selective serotonin reuptake inhibitor medication (SSRI) effects on social behaviors, neurodevelopment and the epigenome
M Gemmel, E Bögi, C Ragan, M Hazlett… - Neuroscience & …, 2018 - Elsevier
Recent research has linked early life exposure to selective serotonin reuptake inhibitor
medications (SSRIs) to modifications of social behaviors in children. Serotonin is a key …
medications (SSRIs) to modifications of social behaviors in children. Serotonin is a key …
Maternal postpartum corticosterone and fluoxetine differentially affect adult male and female offspring on anxiety-like behavior, stress reactivity, and hippocampal …
AR Gobinath, JL Workman, C Chow, SE Lieblich… - …, 2016 - Elsevier
Postpartum depression (PPD) affects approximately 15% of mothers, disrupts maternal care,
and can represent a form of early life adversity for the developing offspring. Intriguingly, male …
and can represent a form of early life adversity for the developing offspring. Intriguingly, male …
Developmental fluoxetine exposure differentially alters central and peripheral measures of the HPA system in adolescent male and female offspring
JL Pawluski, I Rayen, NA Niessen, S Kristensen… - Neuroscience, 2012 - Elsevier
A significant number of women suffer from depression during pregnancy and the postpartum
period. Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat maternal …
period. Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat maternal …