Population genetics of malaria resistance in humans
PW Hedrick - Heredity, 2011 - nature.com
The high mortality and widespread impact of malaria have resulted in this disease being the
strongest evolutionary selective force in recent human history, and genes that confer …
strongest evolutionary selective force in recent human history, and genes that confer …
The global distribution of the Duffy blood group
RE Howes, AP Patil, FB Piel, OA Nyangiri… - Nature …, 2011 - nature.com
Blood group variants are characteristic of population groups, and can show conspicuous
geographic patterns. Interest in the global prevalence of the Duffy blood group variants is …
geographic patterns. Interest in the global prevalence of the Duffy blood group variants is …
Plasmodium vivax clinical malaria is commonly observed in Duffy-negative Malagasy people
D Ménard, C Barnadas, C Bouchier… - Proceedings of the …, 2010 - National Acad Sciences
Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …
Defining the global spatial limits of malaria transmission in 2005
There is no accurate contemporary global map of the distribution of malaria. We show how
guidelines formulated to advise travellers on appropriate chemoprophylaxis for areas of …
guidelines formulated to advise travellers on appropriate chemoprophylaxis for areas of …
Reduced Plasmodium vivax Erythrocyte Infection in PNG Duffy-Negative Heterozygotes
Background Erythrocyte Duffy blood group negativity reaches fixation in African populations
where Plasmodium vivax (Pv) is uncommon. While it is known that Duffy-negative …
where Plasmodium vivax (Pv) is uncommon. While it is known that Duffy-negative …
Resistance to malaria in humans: the impact of strong, recent selection
PW Hedrick - Malaria journal, 2012 - Springer
Malaria is one of the leading causes of death worldwide and has been suggested as the
most potent type of selection in humans in recent millennia. As a result, genes involved in …
most potent type of selection in humans in recent millennia. As a result, genes involved in …