Red blood cell metabolism in vivo and in vitro
Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …
[HTML][HTML] Red blood cell storage time and transfusion: current practice, concerns and future perspectives
M García-Roa, M del Carmen Vicente-Ayuso… - Blood …, 2017 - ncbi.nlm.nih.gov
Red blood cells (RBCs) units are the most requested transfusion product worldwide.
Indications for transfusion include symptomatic anaemia, acute sickle cell crisis, and acute …
Indications for transfusion include symptomatic anaemia, acute sickle cell crisis, and acute …
Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion
RO Francis, A D'Alessandro… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Glucose-6-phosphate dehydrogenase (G6PD) deficiency decreases the
ability of red blood cells (RBCs) to withstand oxidative stress. Refrigerated storage of RBCs …
ability of red blood cells (RBCs) to withstand oxidative stress. Refrigerated storage of RBCs …
Effect of silica-based mesoporous nanomaterials on human blood cells
Different mesoporous nanomaterials (MSNs) are constantly being developed for a range of
therapeutic purposes, but they invariably interact with blood components and may cause …
therapeutic purposes, but they invariably interact with blood components and may cause …
Red blood cell omics and machine learning in transfusion medicine: singularity is near
A D'Alessandro - Transfusion Medicine and Hemotherapy, 2023 - karger.com
Background: Blood transfusion is a life-saving intervention for millions of recipients
worldwide. Over the last 15 years, the advent of high-throughput, affordable omics …
worldwide. Over the last 15 years, the advent of high-throughput, affordable omics …
Oxidative stress and antioxidant defenses during blood processing and storage of erythrocyte concentrates
M Bardyn, JD Tissot, M Prudent - Transfusion Clinique et Biologique, 2018 - Elsevier
Oxidative lesions start accumulating in cells when the oxidant attacks overwhelm the
antioxidant defenses. This review will briefly describe red blood cell storage lesions with …
antioxidant defenses. This review will briefly describe red blood cell storage lesions with …
Metabolic linkage and correlations to storage capacity in erythrocytes from glucose 6-phosphate dehydrogenase-deficient donors
Objective In glucose 6-phosphate dehydrogenase (G6PD) deficiency, decreased NADPH
regeneration in the pentose phosphate pathway and subnormal levels of reduced …
regeneration in the pentose phosphate pathway and subnormal levels of reduced …
The antioxidant capacity of erythrocyte concentrates is increased during the first week of storage and correlated with the uric acid level
Background and Objectives Red blood cells (RBC s) suffer from lesions during cold storage,
depending in part on their ability to counterbalance oxidative stress by activating their …
depending in part on their ability to counterbalance oxidative stress by activating their …
The post-storage performance of RBCs from beta-thalassemia trait donors is related to their storability profile
AT Anastasiadi, EC Paronis, VZ Arvaniti… - International Journal of …, 2021 - mdpi.com
Blood donors with beta-thalassemia traits (βThal+) have proven to be good “storers”, since
their stored RBCs are resistant to lysis and resilient against oxidative/proteotoxic stress. To …
their stored RBCs are resistant to lysis and resilient against oxidative/proteotoxic stress. To …
The intersection of host in vivo metabolism and immune responses to infection with kinetoplastid and apicomplexan parasites
Protozoan parasite infection dramatically alters host metabolism, driven by immunological
demand and parasite manipulation strategies. Immunometabolic checkpoints are often …
demand and parasite manipulation strategies. Immunometabolic checkpoints are often …