Bacterial quorum sensing inhibitors: attractive alternatives for control of infectious pathogens showing multiple drug resistance

AK Bhardwaj, K Vinothkumar… - Recent patents on anti …, 2013 - ingentaconnect.com
Quorum sensing (QS) is a bacterial communication process that depends on the bacterial
population density. It involves small diffusible signaling molecules which activate the …

Production, detection and application perspectives of quorum sensing autoinducer-2 in bacteria

J Zhao, C Quan, L Jin, M Chen - Journal of Biotechnology, 2018 - Elsevier
Abstract Autoinducer-2 (AI-2) is a major signal molecule in bacterial quorum sensing (QS)
besides N-acyl homoserine lactones (AHLs or AI-1). AI-2 mediated QS pathways have been …

[HTML][HTML] Manipulation of the quorum sensing signal AI-2 affects the antibiotic-treated gut microbiota

JA Thompson, RA Oliveira, A Djukovic, C Ubeda… - Cell reports, 2015 - cell.com
The mammalian gut microbiota harbors a diverse ecosystem where hundreds of bacterial
species interact with each other and their host. Given that bacteria use signals to …

[HTML][HTML] Effects of environmental conditions (temperature, pH, and glucose) on biofilm formation of Salmonella enterica serotype Kentucky and virulence gene …

PK Roy, AJW Ha, MFR Mizan, MI Hossain… - Poultry Science, 2021 - Elsevier
Salmonella is a foodborne pathogen and an emerging zoonotic bacterial threat in the food
industry. The aim of this study was to evaluate the biofilm formation by a cocktail culture of 3 …

[HTML][HTML] Curcumin and 10-undecenoic acid as natural quorum sensing inhibitors of LuxS/AI-2 of Bacillus subtilis and LasI/LasR of Pseudomonas aeruginosa

S Fernandes, A Borges, IB Gomes, SF Sousa… - Food Research …, 2023 - Elsevier
The quorum sensing (QS) system is related to cell-to-cell communication as a function of
population density, which regulates several physiological functions including biofilm …

Variability in biofilm formation correlates with hydrophobicity and quorum sensing among Vibrio parahaemolyticus isolates from food contact surfaces and the …

MFR Mizan, IK Jahid, M Kim, KH Lee, TJ Kim, SD Ha - Biofouling, 2016 - Taylor & Francis
Vibrio parahaemolyticus is one of the leading foodborne pathogens causing seafood
contamination. Here, 22 V. parahaemolyticus strains were analyzed for biofilm formation to …

Bacterial communication coordinated behaviors of whole communities to cope with environmental changes

J Pan, J Zhou, X Tang, Y Guo, Y Zhao… - … Science & Technology, 2023 - ACS Publications
Bacterial communication plays an important role in coordinating microbial behaviors in a
community. However, how bacterial communication organizes the entire community for …

Phage-mediated dispersal of biofilm and distribution of bacterial virulence genes is induced by quorum sensing

FS Rossmann, T Racek, D Wobser, J Puchalka… - PLoS …, 2015 - journals.plos.org
The microbiome and the phage meta-genome within the human gut are influenced by
antibiotic treatments. Identifying a novel mechanism, here we demonstrate that bacteria use …

The overlooked role of a biotin precursor for marine bacteria-desthiobiotin as an escape route for biotin auxotrophy

G Wienhausen, S Bruns, S Sultana… - The ISME …, 2022 - academic.oup.com
Biotin (vitamin B7) is involved in a wide range of essential biochemical reactions and a
crucial micronutrient that is vital for many pro-and eukaryotic organisms. The few biotin …

The effect of sublethal concentrations of benzalkonium chloride on the LuxS/AI-2 quorum sensing system, biofilm formation and motility of Escherichia coli

T Yu, M Ma, Y Sun, X Xu, S Qiu, J Yin, L Chen - International Journal of …, 2021 - Elsevier
Escherichia coli can survive improper disinfection processes, which is a potential source of
contamination of food products. Benzalkonium chloride (BC) is a common disinfectant …