Galectin-3: one molecule for an alphabet of diseases, from A to Z

S Sciacchitano, L Lavra, A Morgante, A Ulivieri… - International journal of …, 2018 - mdpi.com
Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Galectin‐3 is a potential mediator for atherosclerosis

Z Gao, Z Liu, R Wang, Y Zheng, H Li… - Journal of immunology …, 2020 - Wiley Online Library
Atherosclerosis is a multifactorial chronic inflammatory arterial disease forming the
pathological basis of many cardiovascular diseases such as coronary heart disease, heart …

Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot

Y Li, T Li, Z Zhou, Y Xiao - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Galectin-3 is a member of the galectin family, widely expressed in immune cells and plays a
role mainly in inflammation, autoimmunity, apoptosis, and chemotaxis. We summarized the …

The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases

G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

The interplay of galectins-1,-3, and-9 in the immune-inflammatory response underlying cardiovascular and metabolic disease

AA Mansour, F Krautter, Z Zhi, AJ Iqbal… - Cardiovascular …, 2022 - Springer
Galectins are β-galactoside-binding proteins that bind and crosslink molecules via their
sugar moieties, forming signaling and adhesion networks involved in cellular …

Glycolipids and lectins in endocytic uptake processes

L Johannes, C Wunder, M Shafaq-Zadah - Journal of molecular biology, 2016 - Elsevier
A host of endocytic processes has been described at the plasma membrane of eukaryotic
cells. Their categorization has most commonly referenced cytosolic machinery, of which the …

Screening and risk assessment of coronary artery disease in patients with type 2 diabetes: an updated review

A Patsouras, P Farmaki, A Garmpi, C Damaskos… - in vivo, 2019 - iv.iiarjournals.org
Current literature indicates that there is a strong correlation between coronary artery disease
(CAD) and type 2 diabetes. The arteriosclerotic progression occurs earlier and in a greater …

Predictive value of Galectin-3 for the occurrence of coronary artery disease and prognosis after myocardial infarction and its association with carotid IMT values in …

A Lisowska, M Knapp, A Tycińska, E Motybel… - Atherosclerosis, 2016 - Elsevier
Abstract Objective The role of Galectin-3 (Gal-3) in atherosclerosis progression has not been
definitely acknowledged. The aim of the study was to establish the following: whether Gal-3 …

Value of galectin-3 in acute myocardial infarction

M Li, Y Yuan, K Guo, Y Lao, X Huang… - American Journal of …, 2020 - Springer
Galectins are an ancient family of lectins characterized by evolutionarily conserved amino
acid sequences and β-galactoside recognition and binding sites. Galectin-3 (Gal-3) is one of …

Is galectin-3 a biomarker, a player—or both—in the presence of coronary atherosclerosis?

G Aksan, Ö Gedikli, K Keskin, G Nar… - Journal of …, 2016 - journals.sagepub.com
Atherosclerosis is a complex process mediated by leukocytes, macrophages and various
inflammatory markers. Galectin-3 is secreted by activated macrophages and is involved in …