Damage associated molecular patterns (DAMPs) are endogenous molecules originate from
damaged cells and tissues with the ability to trigger and/or modify innate immune responses …

Significance: Pulmonary arterial hypertension (PAH) is a progressive disease of the lung
vasculature characterized by the proliferation of all vascular wall cell types, including …

SARS-CoV-2 is causing a pandemic resulting in high morbidity and mortality. COVID-19
patients suffering from acute respiratory distress syndrome (ARDS) are often critically ill and …

Damage-associated molecular patterns, such as HMGB1 (high mobility group box 1), play a
well-recognized role in the development of pulmonary arterial hypertension (PAH), a …

Malaria infection during pregnancy is associated with adverse birth outcomes but underlying
mechanisms are poorly understood. Here, we discuss the impact of malaria in pregnancy on …

We have previously reported that several patients with idiopathic pulmonary hypertension
(PH) had different types of G6PD deficiency. However, the role of G6PD in PH is …

Levels of circulating cell-free hemoglobin are elevated during hemolytic and inflammatory
diseases and contribute to organ dysfunction and severity of illness. Though several studies …

The objective of our study was to contribute to the characterization of monocrotaline-induced
pulmonary arterial hypertension (PAH) in a rat model, with emphasis on the renin …

Pulmonary hypertension in sickle cell disease is an independent predictor of mortality, yet
the pathogenesis of pulmonary vascular disease in chronic hemolytic disorders remains …

Pulmonary hypertension (PH) is recognized to be associated with a number of comorbid
conditions. Based on these associations, PH is classified into 5 groups, considering …