Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

L Brown, JM Wolf, R Prados-Rosales… - Nature Reviews …, 2015 - nature.com
Extracellular vesicles (EVs) are produced by all domains of life. In Gram-negative bacteria,
EVs are produced by the pinching off of the outer membrane; however, how EVs escape the …

Re-engineering extracellular vesicles as smart nanoscale therapeutics

JPK Armstrong, MN Holme, MM Stevens - ACS nano, 2017 - ACS Publications
In the past decade, extracellular vesicles (EVs) have emerged as a key cell-free strategy for
the treatment of a range of pathologies, including cancer, myocardial infarction, and …

Exosomes and other extracellular vesicles in host–pathogen interactions

JS Schorey, Y Cheng, PP Singh, VL Smith - EMBO reports, 2015 - embopress.org
An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …

Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement

C Salomon, S Das, U Erdbrügger, R Kalluri… - Endocrine …, 2022 - academic.oup.com
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …

Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow–derived mesenchymal stem cells and slow age-related degeneration

Q Lei, F Gao, T Liu, W Ren, L Chen, Y Cao… - Science translational …, 2021 - science.org
Stem cell senescence increases alongside the progressive functional declines that
characterize aging. The effects of extracellular vesicles (EVs) are now attracting intense …

[HTML][HTML] Extracellular vesicles: Critical players during cell migration

BH Sung, CA Parent, AM Weaver - Developmental cell, 2021 - cell.com
Cell migration is essential for the development and maintenance of multicellular organisms,
contributing to embryogenesis, wound healing, immune response, and other critical …

Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans

G Vargas, JDB Rocha, DL Oliveira… - Cellular …, 2015 - Wiley Online Library
The release of extracellular vesicles (EV) by fungal organisms is considered an alternative
transport mechanism to trans‐cell wall passage of macromolecules. Previous studies have …

Phenotypic analysis of extracellular vesicles: a review on the applications of fluorescence

MS Panagopoulou, AW Wark, DJS Birch… - Journal of extracellular …, 2020 - Taylor & Francis
Extracellular vesicles (EVs) have numerous potential applications in the field of healthcare
and diagnostics, and research into their biological functions is rapidly increasing. Mainly …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

Secretable small RNAs via outer membrane vesicles in periodontal pathogens

JW Choi, SC Kim, SH Hong… - Journal of dental …, 2017 - journals.sagepub.com
MicroRNAs (miRNAs) have been shown to be major regulators of eukaryotic gene
expression. However, bacterial RNAs comparable in size to eukaryotic miRNAs (18–22 …