Electrolyte's imbalance role in atrial fibrillation: pharmacological management

S Rafaqat, S Rafaqat, H Khurshid, S Rafaqat - International Journal of …, 2022 - Springer
The contribution of the perpetuation of atrial fibrillation is caused by electrical remodeling in
which calcium, sodium and potassium channels could refer to changes in the ion channel …

Analysis on the desert adaptability of indigenous sheep in the southern edge of Taklimakan Desert

C Zhang, C Liu, J Zhang, L Zheng, Q Chang, Z Cui… - Scientific Reports, 2022 - nature.com
The southern margin of the Taklimakan Desert is characterized by low rainfall, heavy
sandstorms, sparse vegetation and harsh ecological environment. The indigenous sheep in …

PRRX1 loss‐of‐function mutations underlying familial atrial fibrillation

XJ Guo, XB Qiu, J Wang, YH Guo… - Journal of the …, 2021 - Am Heart Assoc
Background Atrial fibrillation (AF) is the most common form of clinical cardiac dysrhythmia
responsible for thromboembolic cerebral stroke, congestive heart failure, and death …

[HTML][HTML] A novel PRRX1 loss-of-function variation contributing to familial atrial fibrillation and congenital patent ductus arteriosus

ZP Ke, GF Zhang, YH Guo, YM Sun, J Wang… - … and molecular biology, 2022 - SciELO Brasil
Atrial fibrillation (AF) represents the most common type of sustained cardiac arrhythmia in
humans and confers a significantly increased risk for thromboembolic stroke, congestive …

CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism

M Xu, T Neelands, AS Powers, Y Liu, SD Miller… - Elife, 2024 - elifesciences.org
CLC-2 is a voltage-gated chloride channel that contributes to electrical excitability and ion
homeostasis in many different tissues. Among the nine mammalian CLC homologs, CLC-2 …

KLF15 loss-of-function mutation underlying atrial fibrillation as well as ventricular arrhythmias and cardiomyopathy

N Li, YJ Xu, HY Shi, CX Yang, YH Guo, RG Li, XB Qiu… - Genes, 2021 - mdpi.com
Atrial fibrillation (AF) represents the most common type of clinical cardiac arrhythmia and
substantially increases the risks of cerebral stroke, heart failure and death. Accumulating …

Potential Impacts of Interleukin-17A Promoter Polymorphisms on the EGFR Mutation Status and Progression of Non-Small Cell Lung Cancer in Taiwan

KL Lee, TC Lai, YC Wang, PC Shih, YC Yang… - Genes, 2021 - mdpi.com
Non-small cell lung cancer (NSCLC) is a typical inflammation-associated cancer, and lung
adenocarcinoma (LUAD) is the most common histopathological subtype. Epidermal growth …

Deciphering the Interactions of SARS-CoV-2 Proteins with Human Ion Channels Using Machine-Learning-Based Methods

NS Munjal, D Sapra, KTS Parthasarathi, A Goyal… - Pathogens, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is accountable for the
protracted COVID-19 pandemic. Its high transmission rate and pathogenicity led to health …

Chloride channels and transporters–role in the electrical activity of pacemaker and working myocardium

YA Voronina, AM Karhov… - Uspehi fiziologičeskih …, 2024 - journals.rcsi.science
Chlorine anions have a significant influence on the electrophysiological properties of
excitable tissues, including myocardium. Chlorine anions and transmembrane chloride …

Using human induced pluripotent stem cell derived cardiomyocytes as a model for catecholaminergic polymorphic ventricular tachycardia: Visualizing calcium …

K Ye - 2022 - summit.sfu.ca
Cardiovascular diseases are one of the leading causes of death in the developed world.
Human induced pluripotent stem cell derived cardiomyocytes are a relatively novel model …