Simple Summary mRNA maturation is absolutely required for proper gene expression and,
in recent years, regulators of this process have been found to be tightly intertwined with …

In order to catalyse the splicing of messenger RNA, multiple proteins and RNA components
associate and dissociate in a dynamic highly choreographed process. The Prp19 complex is …

U6 snRNA is one of the uridine-rich non-coding RNAs, abundant and stable in various cells,
function as core particles in the intron-lariat spliceosome (ILS) complex. The Increased Level …

Ribonuclease P (RNase P) is a universal RNA-protein endonuclease that catalyzes
5'precursor-tRNA (ptRNA) processing. The RNase P RNA plays the catalytic role in ptRNA …

Entamoeba histolytica, the causative agent of amebiasis, is the third leading cause of death
among parasitic diseases globally. Its life cycle includes encystation, which has been mostly …

Pre-mRNA splicing is an essential step in gene expression that removes intron sequences
efficiently and accurately to produce a mature mRNA for translation. It is the large and …

This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first
discovered in 1961. These phages played a unique role in early studies of molecular …

Over billions of years of evolution, nature has embraced proteins as the major workhorse
molecules of the cell. However, nearly every aspect of metabolism is dependent upon how …

Toxoplasma gondii, a member of the Apicomplexa phylum, has over 75% of genes with
predicted introns; however, RNA splicing, a major source of post-transcriptional regulation of …

Cell division cycle 5 (Cdc5) is a highly conserved nucleic acid binding protein among
eukaryotes and plays critical roles in development. Cdc5 can simultaneously bind to DNA …