Cannabinoid hyperemesis syndrome: diagnosis, pathophysiology, and treatment—a systematic review

CJ Sorensen, K DeSanto, L Borgelt, KT Phillips… - Journal of Medical …, 2017 - Springer
Cannabinoid hyperemesis syndrome (CHS) is a syndrome of cyclic vomiting associated with
cannabis use. Our objective is to summarize the available evidence on CHS diagnosis …

Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …

The role of the endocannabinoid system in the brain–gut axis

KA Sharkey, JW Wiley - Gastroenterology, 2016 - Elsevier
The actions of cannabis are mediated by receptors that are part of an endogenous
cannabinoid system. The endocannabinoid system (ECS) consists of the naturally occurring …

Cannabinoids and the gut: new developments and emerging concepts

AA Izzo, KA Sharkey - Pharmacology & therapeutics, 2010 - Elsevier
Cannabis has been used to treat gastrointestinal (GI) conditions that range from enteric
infections and inflammatory conditions to disorders of motility, emesis and abdominal pain …

[HTML][HTML] G-protein-coupled receptors in intestinal chemosensation

F Reimann, G Tolhurst, FM Gribble - Cell metabolism, 2012 - cell.com
Food intake is detected by the chemical senses of taste and smell and subsequently by
chemosensory cells in the gastrointestinal tract that link the composition of ingested foods to …

Cannabis use provides symptom relief in patients with inflammatory bowel disease but is associated with worse disease prognosis in patients with Crohn's disease

M Storr, S Devlin, GG Kaplan… - Inflammatory bowel …, 2014 - academic.oup.com
Background Cannabinoids are used by patients with inflammatory bowel disease (IBD) to
alleviate their symptoms. Little is known on patient motivation, benefit, or risks of this …

Action mode of gut motility, fluid and electrolyte transport in chronic constipation

Q Zhao, YY Chen, DQ Xu, SJ Yue, RJ Fu… - Frontiers in …, 2021 - frontiersin.org
Chronic constipation is a common gastrointestinal disorder, with a worldwide incidence of
14–30%. It negatively affects quality of life and is associated with a considerable economic …

The effect of medical cannabis in inflammatory bowel disease: analysis from the UK Medical Cannabis Registry

N Dalavaye, S Erridge, M Nicholas, M Pillai… - Expert Review of …, 2023 - Taylor & Francis
Objectives Cannabis-based medicinal products (CBMPs) have shown promising preclinical
activity in inflammatory bowel disease (IBD). However, clinical trials have not demonstrated …

Endocannabinoid signalling: has it got rhythm?

LK Vaughn, G Denning, KL Stuhr… - British journal of …, 2010 - Wiley Online Library
Endogenous cannabinoid signalling is widespread throughout the body, and considerable
evidence supports its modulatory role in many fundamental physiological processes. The …

An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse

E Pagano, R Capasso, F Piscitelli, B Romano… - Frontiers in …, 2016 - frontiersin.org
Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in
inflammatory bowel disease (IBD) patients. Here, we have investigated the effect of a …