A review of evidence for infection reduction with vancomycin-treated anterior cruciate ligament grafts

LE LeClere, CL Cox, RW Wright - JAAOS-Journal of the American …, 2022 - journals.lww.com
Septic arthritis after anterior cruciate ligament (ACL) reconstruction is a rare but devastating
complication. Several risk factors and known sources of infection have been identified in the …

[HTML][HTML] The role of vancomycin-soaking of the graft in anterior cruciate ligament reconstruction

EC Rodriguez-Merchan, WJ Ribbans - Journal of ISAKOS, 2022 - Elsevier
Approximately 1% of anterior cruciate ligament reconstruction (ACLR) procedures develop
septic arthritis despite intravenous antibiotic prophylaxis and other preventive measures …

Vancomycin soaking is highly cost-effective in primary ACLR infection prevention: a cost-effectiveness study

AP Truong, D Pérez-Prieto, J Byrnes… - … American Journal of …, 2022 - journals.sagepub.com
Background: Although presoaking grafts in vancomycin has been demonstrated to be
effective in observational studies for anterior cruciate ligament reconstruction (ACLR) …

Vancomycin presoaking of anterior cruciate ligament tendon grafts is highly cost-effective for preventing infection

VCB Ruelos, RN Puzzitiello, ME Menendez… - … : The Journal of …, 2021 - Elsevier
Purpose This study aimed to (1) determine whether intraoperative graft soaking with
vancomycin is a cost-effective measure for preventing infection after arthroscopic anterior …

Vancomycin concentrations in synovial fluid do not reach chondrotoxic thresholds after anterior cruciate ligament reconstruction with vancomycin-soaked autologous …

TR Pfeiffer, A Althoff, S Krombholz… - … American Journal of …, 2023 - journals.sagepub.com
Background: Studies have revealed that vancomycin soaking of the anterior cruciate
ligament (ACL) graft can drastically reduce the incidence of postoperative infections after …

Presoaking Grafts in Vancomycin Does Not Impair Graft-Bone Healing in a Rat Anterior Cruciate Ligament Reconstruction Model

R Yoshida, H Koga, J Matsuda… - … American Journal of …, 2024 - journals.sagepub.com
Background: The vancomycin presoaking technique (wherein grafts are treated with a
vancomycin solution [VS] for anterior cruciate ligament reconstruction [ACLR]) reduces the …

Editorial commentary: is it time for the vancomycin wrap to become a universal recommendation for the prevention of septic arthritis following anterior cruciate ligament …

CJ Vertullo - Arthroscopy: The Journal of Arthroscopic & Related …, 2021 - Elsevier
Septic arthritis is a devastating complication of anterior cruciate ligament (ACL)
reconstruction, which can still occur in approximately 1% of patients despite appropriate …

Wrap it! Preventive antimicrobial treatment shows no negative effects on tenocytes and tendons—a comprehensive approach

M Thierbach, M Müller, R Stange… - Journal of Clinical …, 2023 - mdpi.com
Although the rate of infection after the reconstruction of a ruptured anterior cruciate ligament
(ACL) is low, prophylactic incubation of the graft with vancomycin (Vanco-wrap or …

Trends in primary anatomical single-bundle anterior cruciate ligament reconstruction practice in adult patients prevalent among arthroscopy surgeons of six southern …

V Pandey, S Madi, C Thonse, C Joseph… - Indian Journal of …, 2022 - Springer
Background Although guidelines from multiple scientific studies decide the general trend in
ACLR practice, there is often a variation between scientific guidelines and actual practice …

Editorial commentary: vancomycin soaking of the graft in anterior cruciate ligament reconstruction: a concept on the way to becoming the new gold standard

TR Pfeiffer - Arthroscopy: The Journal of Arthroscopic & Related …, 2021 - Elsevier
An increasing number of surgeons adopt the concept of vancomycin soaking of the graft in
anterior cruciate ligament reconstruction and report drastically reduced numbers of …