The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a
wide array of signaling events, leading to protective (eg, cytoskeletal rearrangement) and …

Inflammatory diseases, whether caused by excessive stress on certain tissues/parts of the
body or arising from infections accompanying autoimmune or secondary diseases, have …

The respective life histories of human subjects and mice are well defined and describe a
unique story of evolutionary conservation extending from sequence identity within the …

A series of ursodeoxycholic acid (UDCA)-cinnamic acid hybrids were designed and
synthesized. The anti-inflammatory activity of these derivatives was screened through …

The use of natural compounds is becoming increasingly popular among patients, and there
is a renewed interest among scientists in nature-based bioactive agents. Traditionally …

Unbiased genetic approaches, especially genome-wide association studies, have identified
novel genetic targets in the pathogenesis of asthma, but so far these targets account for only …

Inflammation is favorable in most cases, because it is a kind of body defensive response to
external stimuli; sometimes, inflammation is also harmful, such as attacks on the body's own …

Abstract Two new series of 1, 5-diaryl pyrazoles (5a, 5b, 7a, 7b and 10) and 1, 5-diaryl
pyrazoline (12a and 12b) were prepared as both Cyclooxygenase-2 and 15-lipoxygenase …

A series of novel acrylic acid derivatives bearing at the 3 position thienyl, furfuryl and 3, 5-
ditert-butyl-4-hydroxyphenyl substituents have been designed, synthesized and tested as …

In this study, series of ring-substituted 2-styrylquinazolin-4 (3 H)-one and 4-chloro-2-
styrylquinazoline derivatives were prepared. The syntheses of the discussed compounds …