Soft actuators for soft robotic applications: A review
Soft robotics technologies are paving the way toward robotic abilities which are vital for a
wide range of applications, including manufacturing, manipulation, gripping, human …
wide range of applications, including manufacturing, manipulation, gripping, human …
Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials
Y Cheng, C He, M Wang, X Ma, F Mo, S Yang… - Signal transduction and …, 2019 - nature.com
Epigenetic alternations concern heritable yet reversible changes in histone or DNA
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …
Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities
Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …
junctions and polarity while acquiring mesenchymal properties and invasive ability …
Structure and function of SET and MYND domain-containing proteins
N Spellmon, J Holcomb, L Trescott… - International journal of …, 2015 - mdpi.com
SET (Suppressor of variegation, Enhancer of Zeste, Trithorax) and MYND (Myeloid-Nervy-
DEAF1) domain-containing proteins (SMYD) have been found to methylate a variety of …
DEAF1) domain-containing proteins (SMYD) have been found to methylate a variety of …
Smyd3 is a transcriptional potentiator of multiple cancer-promoting genes and required for liver and colon cancer development
ME Sarris, P Moulos, A Haroniti, A Giakountis… - Cancer cell, 2016 - cell.com
Smyd3 is a protein methyltransferase implicated in cancer development. Here we show that
Smyd3 expression in mice is required for chemically induced liver and colon cancer …
Smyd3 expression in mice is required for chemically induced liver and colon cancer …
Theileria-transformed bovine leukocytes have cancer hallmarks
The genus Theileria includes tick-transmitted apicomplexan parasites of ruminants with
substantial economic impact in endemic countries. Some species, including Theileria parva …
substantial economic impact in endemic countries. Some species, including Theileria parva …
JARID1D is a suppressor and prognostic marker of prostate cancer invasion and metastasis
Entire or partial deletions of the male-specific Y chromosome are associated with
tumorigenesis, but whether any male-specific genes located on this chromosome play a …
tumorigenesis, but whether any male-specific genes located on this chromosome play a …
Targeting macrophage histone H3 modification as a leishmania strategy to dampen the NF-κB/NLRP3-mediated inflammatory response
H Lecoeur, E Prina, T Rosazza, K Kokou, P N'Diaye… - Cell reports, 2020 - cell.com
Aberrant macrophage activation during intracellular infection generates immunopathologies
that can cause severe human morbidity. A better understanding of immune subversion …
that can cause severe human morbidity. A better understanding of immune subversion …
SMYD3 promotes the epithelial–mesenchymal transition in breast cancer
C Fenizia, C Bottino, S Corbetta, R Fittipaldi… - Nucleic acids …, 2019 - academic.oup.com
SMYD3 is a methylase previously linked to cancer cell invasion and migration. Here we
show that SMYD3 favors TGFβ-induced epithelial–mesenchymal transition (EMT) in …
show that SMYD3 favors TGFβ-induced epithelial–mesenchymal transition (EMT) in …
SMYD3: an oncogenic driver targeting epigenetic regulation and signaling pathways
C Bottino, A Peserico, C Simone, G Caretti - Cancers, 2020 - mdpi.com
SMYD3 is a member of the SMYD lysine methylase family and plays an important role in the
methylation of various histone and non-histone targets. Aberrant SMYD3 expression …
methylation of various histone and non-histone targets. Aberrant SMYD3 expression …