Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis

A Petzold, JF de Boer, S Schippling… - The Lancet …, 2010 - thelancet.com
Optical coherence tomography (OCT) is a new method that could aid analysis of
neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre …

Optical coherence tomography as a biomarker for diagnosis, progression, and prognosis of neurodegenerative diseases

M Satue, J Obis, MJ Rodrigo, S Otin… - Journal of …, 2016 - Wiley Online Library
Neurodegenerative diseases present a current challenge for accurate diagnosis and for
providing precise prognostic information. Developing imaging biomarkers for multiple …

Retinal damage in multiple sclerosis disease subtypes measured by high‐resolution optical coherence tomography

T Oberwahrenbrock, S Schippling… - Multiple sclerosis …, 2012 - Wiley Online Library
Background. Optical coherence tomography (OCT) has facilitated characterisation of retinal
alterations in MS patients. Only scarce and in part conflicting data exists on different MS …

Optical coherence tomography differs in neuromyelitis optica compared with multiple sclerosis

RT Naismith, NT Tutlam, J Xu, EC Klawiter… - Neurology, 2009 - AAN Enterprises
Background: Neuromyelitis optica (NMO) is associated with destructive inflammatory
lesions, resulting in necrosis and axonal injury. Disability from multiple sclerosis (MS) is due …

Association of retinal and macular damage with brain atrophy in multiple sclerosis

J Dörr, KD Wernecke, M Bock, G Gaede, JT Wuerfel… - PLoS …, 2011 - journals.plos.org
Neuroaxonal degeneration in the central nervous system contributes substantially to the
long term disability in multiple sclerosis (MS) patients. However, in vivo determination and …

Optical coherence tomography is less sensitive than visual evoked potentials in optic neuritis

RT Naismith, NT Tutlam, J Xu, JB Shepherd… - Neurology, 2009 - AAN Enterprises
Objectives: Determine the utility of optical coherence tomography (OCT) to detect clinical
and subclinical remote optic neuritis (ON), its relationship to clinical characteristics of ON …

Optical coherence tomography of the retina: applications in neurology

P Jindahra, TR Hedges… - Current opinion in …, 2010 - journals.lww.com
The findings indicate loss of retinal ganglion cells and may reflect degenerative change in
the brain in these conditions. The retinal nerve fibre layer thickness may be used as a …

Degeneration of retinal layers in multiple sclerosis subtypes quantified by optical coherence tomography

P Albrecht, M Ringelstein, AK Müller… - Multiple Sclerosis …, 2012 - journals.sagepub.com
Background: Optical coherence tomography can be used to assess retinal degeneration in
multiple sclerosis (MS). Thinning of the retinal nerve fibre layer and macular thickness have …

Early high-dose intravenous methylprednisolone is effective in preserving retinal nerve fiber layer thickness in patients with neuromyelitis optica

M Nakamura, T Nakazawa, H Doi, T Hariya… - Graefe's archive for …, 2010 - Springer
Background Neuromyelitis optica (NMO) is a recurring inflammatory neurological disease
characterized by severe optic neuritis and myelitis. The purpose of this study was to …

Axonal loss of retinal neurons in multiple sclerosis associated with optic radiation lesions

A Klistorner, P Sriram, N Vootakuru, C Wang… - Neurology, 2014 - AAN Enterprises
Objective: To investigate the potential links between thinning of retinal ganglion cell axons in
eyes of patients with multiple sclerosis (MS) without past optic neuritis (ON) and MS-related …