Major depressive disorder (MDD) is a psychiatric disorder with increasing prevalence
worldwide. It is a leading cause of disability and suicide, severely affecting physical and …

Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …

Current approaches to the treatment of schizophrenia have mainly focused on the protein-
coding part of the genome; in this context, the roles of microRNAs have received less …

Schizophrenia (SCZ) is a polygenic, complex mental disorder of which a diagnosis is often
made based on psychiatric history and clinical observation with few available objectives and …

Childhood maltreatment (CM) is regarded as an important risk factor for major depressive
disorder (MDD). However, the neural links corresponding to the process of early CM …

We explore how functional genomics approaches that integrate datasets from human and
non-human model systems can improve our understanding of the effect of gene …

Chronic pain is highly prevalent and burdensome, affecting millions of people worldwide.
Although it emerges at any point in life, it often manifests in adolescence. Given that …

Exposure to stress can accelerate maturation and hasten reproduction. Although potentially
adaptive, the trade-off is higher risk for morbidity and mortality. In humans, the …

Epidemiological studies from the last century have drawn strong associations between
paternal life experiences and offspring health and disease outcomes. Recent studies have …

Aims: The aim of this study was to assess regional-and sex-dependent changes in miRNA
expression resulting from early-life stress (ELS). Materials and methods: Small RNA …