Targeting breast cancer stem cells through retinoids: a new hope for treatment

N Jan, S Sofi, H Qayoom, BU Haq, A Shabir… - Critical Reviews in …, 2023 - Elsevier
Breast cancer is a complex and diverse disease accounting for nearly 30% of all cancers
diagnosed in females. But unfortunately, patients develop resistance to the existing …

Innovative nanotheranostics: Smart nanoparticles based approach to overcome breast cancer stem cells mediated chemo‐and radioresistances

P Kola, PKB Nagesh, PK Roy, K Deepak… - Wiley …, 2023 - Wiley Online Library
The alarming increase in the number of breast cancer patients worldwide and the increasing
death rate indicate that the traditional and current medicines are insufficient to fight against …

[HTML][HTML] Hyaluronic acid (HA)-coated naproxen-nanoparticles selectively target breast cancer stem cells through COX-independent pathways

E Espinosa-Cano, M Huerta-Madronal… - Materials Science and …, 2021 - Elsevier
Cytotoxic chemotherapy continues to be the main therapeutic option for patients with
metastatic breast cancer. Several studies have reported a significant association between …

Tumorigenic risk of Angelica sinensis on ER-positive breast cancer growth through ER-induced stemness in vitro and in vivo

H Zhu, J You, Y Wen, L Jia, F Gao, K Ganesan… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance The root of Angelica sinensis is widely used in traditional
Chinese Medicine for relieving gynecological discomforts among the women population …

miR-145–5p as a predictive biomarker for breast cancer stemness by computational clinical investigation

D Rajarajan, B Kaur, D Penta, J Natesh… - Computers in Biology …, 2021 - Elsevier
Background Breast tumors enriched with breast cancer stem cells (BCSCs), play a crucial
role in metastasis and tumor relapse. Hence, targeting BCSCs may lead to efficacious breast …

Molecular pathways and therapeutic targets linked to triple-negative breast cancer (TNBC)

M Mustafa, K Abbas, M Alam, W Ahmad… - Molecular and Cellular …, 2024 - Springer
Cancer is a group of diseases characterized by uncontrolled cellular growth, abnormal
morphology, and altered proliferation. Cancerous cells lose their ability to act as anchors …

MicroRNAs, a promising target for breast cancer stem cells

PK Das, MA Siddika, SY Asha, S Aktar… - Molecular Diagnosis & …, 2020 - Springer
Reactivation of the stem cell programme in breast cancer is significantly associated with
persistent cancer progression and therapeutic failure. Breast cancer stem cells (BCSCs) are …

Nanosized drug delivery systems for breast cancer stem cell targeting

L Lv, Y Shi, J Wu, G Li - International Journal of Nanomedicine, 2021 - Taylor & Francis
Breast cancer stem cells (BCSCs), also known as breast cancer initiating cells, are reported
to be responsible for the initiation, progression, therapeutic resistance, and relapse of breast …

[HTML][HTML] Therapeutic strategies against cancer stem cells in esophageal carcinomas

PK Das, F Islam, RA Smith, AK Lam - Frontiers in Oncology, 2021 - frontiersin.org
Cancer stem cells (CSCs) in esophageal cancer have a key role in tumor initiation,
progression and therapy resistance. Novel therapeutic strategies to target CSCs are being …

Stem cells: Therapeutic implications in chemotherapy and radiotherapy resistance in cancer therapy

T Patil, SS Rohiwal, AP Tiwari - Current Stem Cell Research & …, 2023 - ingentaconnect.com
Cancer stem cells (CSCs) are transformed forms of normal stem cells within heterogeneous
mixture of cancer cells. These are mainly responsible for the recurrence of cancer after …