Runs of homozygosity: current knowledge and applications in livestock

E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …

The transition period updated: A review of the new insights into the adaptation of dairy cows to the new lactation

M Mezzetti, L Cattaneo, MM Passamonti, V Lopreiato… - Dairy, 2021 - mdpi.com
Recent research on the transition period (TP) of dairy cows has highlighted the pivotal role
of immune function in affecting the severity of metabolic challenges the animals face when …

The distribution of runs of homozygosity and selection signatures in six commercial meat sheep breeds

DC Purfield, S McParland, E Wall, DP Berry - PloS one, 2017 - journals.plos.org
Domestication and the subsequent selection of animals for either economic or
morphological features can leave a variety of imprints on the genome of a population …

Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle

M Forutan, S Ansari Mahyari, C Baes, N Melzer… - BMC genomics, 2018 - Springer
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …

Detect runs of homozygosity and runs of heterozygosity in diploid genomes

F Biscarini, P Cozzi, G Gaspa, G Marras - 2019 - iris.unito.it
detectRUNS is a R package for the detection of runs of homozygosity (ROH/ROHom) and of
heterozygosity (ROHet, aka “heterozygosity-rich regions”) in diploid genomes. ROH/ROHom …

Genetic diversity and signatures of selection in various goat breeds revealed by genome-wide SNP markers

LF Brito, JW Kijas, RV Ventura, M Sargolzaei… - BMC genomics, 2017 - Springer
Background The detection of signatures of selection has the potential to elucidate the
identities of genes and mutations associated with phenotypic traits important for livestock …

Estimation of inbreeding using pedigree, 50k SNP chip genotypes and full sequence data in three cattle breeds

Q Zhang, MPL Calus, B Guldbrandtsen, MS Lund… - BMC genetics, 2015 - Springer
Background Levels of inbreeding in cattle populations have increased in the past due to the
use of a limited number of bulls for artificial insemination. High levels of inbreeding lead to …

Genomic inbreeding estimation in small populations: evaluation of runs of homozygosity in three local dairy cattle breeds

S Mastrangelo, M Tolone, R Di Gerlando, L Fontanesi… - Animal, 2016 - cambridge.org
In the local breeds with small population size, one of the most important problems is the
increase of inbreeding coefficient (F). High levels of inbreeding lead to reduced genetic …

Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle

E Peripolli, NB Stafuzza, DP Munari, ALF Lima… - BMC genomics, 2018 - Springer
Background Runs of homozygosity (ROH) are continuous homozygous segments of the
DNA sequence. They have been applied to quantify individual autozygosity and used as a …

[HTML][HTML] 基于SNP 芯片的丫杈猪保种群体遗传结构研究

陶璇, 杨雪梅, 梁艳, 刘一辉, 汪勇, 孔繁晶, 雷云峰… - 畜牧兽医学报, 2023 - html.rhhz.net
旨在研究丫杈猪保种群体的遗传多样性, 亲缘关系和家系结构. 本研究采用“中芯一号”
芯片检测了166 头丫杈种猪的单核苷酸多态性(single nucleotide polymorphism, SNP); …