The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …

Cells produce reactive oxygen species (ROS) as a metabolic by-product. ROS molecules
trigger oxidative stress as a feedback response that significantly initiates biological …

Fructose as a daily sweetener is widely recognized as a risk catalyst for nonalcoholic fatty
liver disease (NAFLD). The aim of current study is to evaluate the effects and molecular …

Oxidative stress and inflammation in neuron-glia system are key factors in the pathogenesis
of neurodegenerative diseases. As synthetic drugs may cause side effects, natural products …

High mitochondrial oxidative phosphorylation (mt-OXPHOS) levels are required to supply
the ATP necessary for follicle-stimulating hormone (FSH)-induced granulosa cell …

High-fat (HF) diets cause obesity, gut microbial dysbiosis and associated disorders and
inflammatory bowel disease (IBD) due to increased intestinal permeability, which is an …

Acute as well as chronic disorders of the nervous system lead to significant morbidity and
mortality for millions of individuals globally. Given the ability to govern stem cell proliferation …

Anthocyanins, a group of polyphenolic pigments, have been proved to possess various
bioactivities. However, they are unstable in the small intestine and absorbed with low …

Sulfuretin, one of the major flavonoid glycosides found in the stem bark of Albizzia julibrissin
and heartwood of Rhus verniciflua, is a known anti-oxidant. We previously demonstrated …

Mammalian forkhead transcription factors of the O class (FoxO) are exciting targets under
consideration for the development of new clinical entities to treat metabolic disorders and …