T resident helper cells promote humoral responses in the lung
N Swarnalekha, D Schreiner, LC Litzler, S Iftikhar… - Science …, 2021 - science.org
Influenza is a deadly and costly infectious disease, even during flu seasons when an
effective vaccine has been developed. To improve vaccines against respiratory viruses, a …
effective vaccine has been developed. To improve vaccines against respiratory viruses, a …
Gene expression phylogenies and ancestral transcriptome reconstruction resolves major transitions in the origins of pregnancy
Structural and physiological changes in the female reproductive system underlie the origins
of pregnancy in multiple vertebrate lineages. In mammals, the glandular portion of the lower …
of pregnancy in multiple vertebrate lineages. In mammals, the glandular portion of the lower …
[HTML][HTML] RORα is critical for mTORC1 activity in T cell-mediated colitis
Inflammatory bowel disease (IBD) is multi-factorial chronic intestinal inflammation driven by
pathogenic T cells, among which a large portion of patients are resistant to current anti …
pathogenic T cells, among which a large portion of patients are resistant to current anti …
ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 …
Angiotensin-converting enzyme-2 (ACE2) receptor has been identified as the key adhesion
molecule for the transmission of the SARS-CoV-2. However, there is no evidence that …
molecule for the transmission of the SARS-CoV-2. However, there is no evidence that …
Redefining CD4 T cell residency: Helper T cells orchestrate protective humoral immunity in the lung
N Swarnalekha, D Schreiner, LC Litzler, S Iftikhar… - BioRxiv, 2020 - biorxiv.org
Influenza is a severe and acute respiratory pathogen, and a significant cause for morbidity,
particularly in young children and the elderly. Following influenza infection, clonally …
particularly in young children and the elderly. Following influenza infection, clonally …
RORα enforces stability of the T-helper-17 cell effector program
Summary T helper 17 (Th17) cells regulate mucosal barrier defenses, but also promote
multiple autoinflammatory diseases. Although many molecular determinants of Th17 cell …
multiple autoinflammatory diseases. Although many molecular determinants of Th17 cell …