Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
Faecalibacterium: a bacterial genus with promising human health applications
In humans, many diseases are associated with alterations in gut microbiota, namely
increases or decreases in the abundance of specific bacterial groups. One example is the …
increases or decreases in the abundance of specific bacterial groups. One example is the …
Targeting the gut microbiota for cancer therapy
Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …
[HTML][HTML] Roseburia intestinalis: A Beneficial Gut Organism From the Discoveries in Genus and Species
K Nie, K Ma, W Luo, Z Shen, Z Yang, M Xiao… - Frontiers in cellular …, 2021 - frontiersin.org
Roseburia intestinalis is an anaerobic, Gram-positive, slightly curved rod-shaped flagellated
bacterium that produces butyrate in the colon. R. intestinalis has been shown to prevent …
bacterium that produces butyrate in the colon. R. intestinalis has been shown to prevent …
The microbial landscape of colorectal cancer
MT White, CL Sears - Nature Reviews Microbiology, 2024 - nature.com
Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …
need of improved prevention and treatment strategies. As our understanding of CRC grows …
[HTML][HTML] Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
Hot and cold tumors: Immunological features and the therapeutic strategies
L Wang, H Geng, Y Liu, L Liu, Y Chen, F Wu, Z Liu… - MedComm, 2023 - Wiley Online Library
Abstract The “hotness” or “coldness” of the tumors are determined by the information of the
cancer cells themselves, tumor immune characteristics, tumor microenvironment, and …
cancer cells themselves, tumor immune characteristics, tumor microenvironment, and …
[HTML][HTML] Machine learning approaches in microbiome research: challenges and best practices
Microbiome data predictive analysis within a machine learning (ML) workflow presents
numerous domain-specific challenges involving preprocessing, feature selection, predictive …
numerous domain-specific challenges involving preprocessing, feature selection, predictive …
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity
Y Choi, JN Lichterman, LA Coughlin, N Poulides… - Science …, 2023 - science.org
Gut microbiota, specifically gut bacteria, are critical for effective immune checkpoint
blockade therapy (ICT) for cancer. The mechanisms by which gut microbiota augment …
blockade therapy (ICT) for cancer. The mechanisms by which gut microbiota augment …
[HTML][HTML] Intratumor microbiome in cancer progression: current developments, challenges and future trends
J Liu, Y Zhang - Biomarker Research, 2022 - Springer
Cancer is a complicated disease attributed to multifactorial changes, which causes
difficulties with treatment strategies. Various factors have been regarded as the main …
difficulties with treatment strategies. Various factors have been regarded as the main …