Recent perspective of polymeric biomaterial in tissue engineering–a review
Tissue engineering represents an advanced approach to treating patients who have
suffered tissue or organ loss or failure, with the ultimate goals of tissue restoration and …
suffered tissue or organ loss or failure, with the ultimate goals of tissue restoration and …
Exploring the properties and potential of the neural extracellular matrix for next‐generation regenerative therapies
JA Ortega, GP Soares de Aguiar… - Wiley …, 2024 - Wiley Online Library
The extracellular matrix (ECM) is a dynamic and complex network of proteins and molecules
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …
Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids
P Saglam-Metiner, U Devamoglu, Y Filiz… - Communications …, 2023 - nature.com
The bioengineerined and whole matured human brain organoids stand as highly valuable
three-dimensional in vitro brain-mimetic models to recapitulate in vivo brain development …
three-dimensional in vitro brain-mimetic models to recapitulate in vivo brain development …
Humanized brain organoids-on-chip integrated with sensors for screening neuronal activity and neurotoxicity
The complex structure and function of the human central nervous system that develops from
the neural tube made in vitro modeling quite challenging until the discovery of brain …
the neural tube made in vitro modeling quite challenging until the discovery of brain …
Biosensor integrated brain-on-a-chip platforms: progress and prospects in clinical translation
Because of the brain's complexity, developing effective treatments for neurological disorders
is a formidable challenge. Research efforts to this end are advancing as in vitro systems …
is a formidable challenge. Research efforts to this end are advancing as in vitro systems …
Differentiation of neurons, astrocytes, oligodendrocytes and microglia from human induced pluripotent stem cells to form neural tissue-on-chip: a neuroinflammation …
P Saglam-Metiner, E Duran, L Sabour-Takanlou… - Stem Cell Reviews and …, 2024 - Springer
Advances in stem cell (SC) technology allow the generation of cellular models that
recapitulate the histological, molecular and physiological properties of humanized in vitro …
recapitulate the histological, molecular and physiological properties of humanized in vitro …
Constructing Tumor Organoid-like Tissue for Reliable Drug Screening Using Liver-Decellularized Extracellular Matrix Scaffolds
Z Chen, L Long, J Wang, W Li, A Wang, RK Kankala… - ACS …, 2024 - ACS Publications
The interplay between cells and their microenvironments plays a pivotal role in in vitro drug
screening. Creating an environment that faithfully mimics the conditions of tumor cells within …
screening. Creating an environment that faithfully mimics the conditions of tumor cells within …
Bioinspired microstructures through decellularization of plants for tissue engineering applications
Y Arslan, A Paradiso, N Celiktas, T Erdogan… - European Polymer …, 2023 - Elsevier
In nature, various patterns such as branches, stripes, spirals, and hexagons exist in
biological and natural systems, from nano-to macro-scale. These hierarchical structures …
biological and natural systems, from nano-to macro-scale. These hierarchical structures …
Comprehensive transcriptomic investigation of Rett syndrome reveals increasing complexity trends from induced pluripotent stem cells to neurons with implications for …
YC Odabasi, S Yanasik, P Saglam-Metiner… - ACS …, 2023 - ACS Publications
Rett syndrome (RTT) is a rare genetic neurodevelopmental disorder that has no cure apart
from symptomatic treatments. While intense research efforts are required to fulfill this unmet …
from symptomatic treatments. While intense research efforts are required to fulfill this unmet …
The Application of Biomaterial‐Based Spinal Cord Tissue Engineering
Advancements in biomaterial‐based spinal cord tissue engineering technology have
profoundly influenced regenerative medicine, providing innovative solutions for both spinal …
profoundly influenced regenerative medicine, providing innovative solutions for both spinal …