A review on mechanism of inhibition of advanced glycation end products formation by plant derived polyphenolic compounds
Advanced glycation end products (AGEs) are naturally occurring biomolecules formed by
interaction of reducing sugars with biomolecules such as protein and lipids etc., Long term …
interaction of reducing sugars with biomolecules such as protein and lipids etc., Long term …
Current biomedical use of copper chelation therapy
S Baldari, G Di Rocco, G Toietta - International journal of molecular …, 2020 - mdpi.com
Copper is an essential microelement that plays an important role in a wide variety of
biological processes. Copper concentration has to be finely regulated, as any imbalance in …
biological processes. Copper concentration has to be finely regulated, as any imbalance in …
[HTML][HTML] Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
X Wang, X Chen, W Zhou, H Men, T Bao, Y Sun… - … Pharmaceutica Sinica B, 2022 - Elsevier
Herein, we define the role of ferroptosis in the pathogenesis of diabetic cardiomyopathy
(DCM) by examining the expression of key regulators of ferroptosis in mice with DCM and a …
(DCM) by examining the expression of key regulators of ferroptosis in mice with DCM and a …
6‐Gingerol alleviates Ferroptosis and inflammation of diabetic cardiomyopathy via the Nrf2/HO‐1 pathway
S Wu, J Zhu, G Wu, Z Hu, P Ying, Z Bao… - Oxidative medicine …, 2022 - Wiley Online Library
Background. Diabetes mellitus (DM) can induce cardiomyocyte injury and lead to diabetic
cardiomyopathy (DCM) which presently has no specific treatments and consequently …
cardiomyopathy (DCM) which presently has no specific treatments and consequently …
Inflammatory mechanisms in the pathophysiology of diabetic peripheral neuropathy (DN)—new aspects
P Baum, KV Toyka, M Blüher, J Kosacka… - International Journal of …, 2021 - mdpi.com
The pathogenesis of diabetic neuropathy is complex, and various pathogenic pathways
have been proposed. A better understanding of the pathophysiology is warranted for …
have been proposed. A better understanding of the pathophysiology is warranted for …
Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms
EE Battin, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
It is well known that oxidation caused by reactive oxygen species (ROS) is a major cause of
cellular damage and death and has been implicated in cancer, neurodegenerative, and …
cellular damage and death and has been implicated in cancer, neurodegenerative, and …
Dicarbonyls and advanced glycation end-products in the development of diabetic complications and targets for intervention
S Brings, T Fleming, M Freichel… - International journal of …, 2017 - mdpi.com
Advanced glycation end-products (AGEs) are non-enzymatic protein and amino acid
adducts as well as DNA adducts which form from dicarbonyls and glucose. AGE formation is …
adducts as well as DNA adducts which form from dicarbonyls and glucose. AGE formation is …
The role of zinc and copper in insulin resistance and diabetes mellitus
G Bjørklund, M Dadar, L Pivina… - Current medicinal …, 2020 - ingentaconnect.com
The prevalence of Type 2 Diabetes Mellitus (T2DM) is internationally ever-growing.
Therefore, prevention, diagnostics, and control of insulin resistance and T2DM are of …
Therefore, prevention, diagnostics, and control of insulin resistance and T2DM are of …
Nutritional and functional properties of gluten-free flours
This study characterized and compared 13 gluten-free (GF) flours (rice, brown rice, maize,
oat, millet, teff, amaranth, buckwheat, quinoa, chickpea, gram, tiger nut, and plantain) for …
oat, millet, teff, amaranth, buckwheat, quinoa, chickpea, gram, tiger nut, and plantain) for …
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …