Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …

Osmotin is a stress responsive antifungal protein belonging to the pathogenesis-related
(PR)-5 family that confers tolerance to both biotic and abiotic stresses in plants. Protective …

Aging is a major factor involved in neurological impairments, decreased anti-oxidant
activities, and enhanced neuroinflammation. D-galactose (D-gal) has been considered an …

Abstract Toll-like receptor 4 (TLR4) signaling in the brain mediates autoimmune responses
and induces neuroinflammation that results in neurodegenerative diseases, such as …

Extensive evidence has indicated that a high rate of cholesterol biogenesis and abnormal
neuronal energy metabolism play key roles in Alzheimer's disease (AD) pathogenesis. Here …

The pathological hallmarks of Alzheimer's disease (AD) include amyloid beta (Aβ)
accumulation, neurofibrillary tangle formation, synaptic dysfunction and neuronal loss. In this …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …

The aim of the current study was to explore the underlying neuroprotective mechanisms of
curcumin (50 mg/kg, for six weeks) against ethanol (5 mg/kg ip, for six weeks) induced …

Alzheimer's disease (AD) is the most prevalent age-related neurodegenerative disease,
pathologically characterized by the accumulation of aggregated amyloid beta (Aβ) in the …

The present study aims to determine the neuroprotective effect of Bergenin against spatial
memory deficit associated with neurodegeneration. Preliminarily, the protective effect of …