Synthesis and antioxidant activities of phenol derivatives from 1, 6-bis (dimethoxyphenyl) hexane-1, 6-dione

T Artunc, A Menzek, P Taslimi, I Gulcin, C Kazaz… - Bioorganic …, 2020 - Elsevier
Abstract Starting from the compound (3, 4-dimethoxyphenyl)(2-(3, 4-dimethoxyphenyl)
cyclopent-1-en-1-yl) methanone (4), two diols and three tetrol derivatives were synthesised …

Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester

M Boztas, P Taslimi, MA Yavari, I Gulcin, E Sahin… - Bioorganic …, 2019 - Elsevier
Abstract Trans-(1R*, 2R*, 3R*)-Ethyl 2-(3, 4-dimethoxyphenyl)-3-methylcyclopropane-1-
carboxylate (6) and its cis isomer 7 were obtained from the reaction of the methyl isoeugenol …

Synthesis and antioxidant properties of (3, 4‐dihydroxyphenyl)(2, 3, 4‐trihydroxyphenyl) methanone and its derivatives

Y Cetinkaya, H Göçer, A Menzek… - Archiv der …, 2012 - Wiley Online Library
Dihydroxyphenyl)(2, 3, 4‐trihydroxyphenyl) methanone (5) and its two derivatives with
bromine were synthesized from reactions such as bromination and demethylation of (3, 4 …

The first synthesis and antioxidant and anticholinergic activities of 1-(4, 5-dihydroxybenzyl) pyrrolidin-2-one derivative bromophenols including natural products

M Rezai, C Bayrak, P Taslimi… - Turkish journal of …, 2018 - journals.tubitak.gov.tr
We report herein the first synthesis of biologically active natural bromophenols, namely 1-(2,
3, 6-tribromo-4, 5-dihydroxybenzyl) pyrrolidin-2-one (2), 2RS-1-(2, 3-dibromo-4, 5 …

(3, 4-Dihydroxyphenyl)(2, 3, 4-trihydroxyphenyl) methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors

M Nar, Y Çetinkaya, İ Gülçin… - Journal of Enzyme …, 2013 - Taylor & Francis
In this study, we have synthesised (3, 4-dihydroxyphenyl)(2, 3, 4-trihydroxyphenyl)
methanone and a series of its derivatives (5, 13–16) and tested the ability of these …

Synthesis and carbonic anhydrase isoenzymes inhibitory effects of brominated diphenylmethanone and its derivatives

Y Çetinkaya, H Göçer, İ Gülçin… - Archiv Der Pharmazie, 2014 - Wiley Online Library
Known and novel derivatives including CO, Br, and OH (benzylic and phenolic), and the
corresponding benzylic alcohols of (3, 4‐dimethoxyphenyl)(2, 3, 4‐dimethoxyphenyl) …

Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: Vidalol B

HT Balaydın, M Şentürk, S Göksu, A Menzek - European journal of …, 2012 - Elsevier
A series of bisphenol, bromophenol, and methoxyphenol derivatives (2–24) including the
natural bromophenols vidalol B, 3, 4, 6-tribromo-5-(2, 5-dibromo-3, 4-dihydroxybenzyl) …

Synthesis of 4‐[2‐(3, 4‐dimethoxybenzyl) cyclopentyl]‐1, 2‐dimethoxybenzene derivatives and evaluations of their carbonic anhydrase isoenzymes inhibitory effects

T Artunc, Y Cetinkaya, H Göçer, İ Gülçin… - Chemical biology & …, 2016 - Wiley Online Library
Rearrangement of 1, 6‐bis (3, 4‐dimethoxyphenyl) hexane‐1, 6‐dione (8) gave two isomeric
products having cyclopentene moiety. Starting from the major product (3, 4 …

Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives

HT Balaydın, M Şentürk, A Menzek - Bioorganic & medicinal chemistry …, 2012 - Elsevier
The Naturally occurring novel cyclohexanonyl bromophenol 2 (R)-2-(2, 3, 6-tribromo-4, 5-
dihydroxybenzyl) cyclohexanone (4) was synthesized as a racemic compound …

Synthesis and carbonic anhydrase isoenzymes I and II inhibitory effects of novel benzylamine derivatives

Y Cetinkaya, H Göçer, S Göksu… - Journal of Enzyme …, 2014 - Taylor & Francis
Synthesis and carbonic anhydrase inhibitory properties of novel diarylmethylamines 22–25
and sulfonamide derivatives 26–28 were investigated. Acylation of methoxy-substituted …