Are trade‐offs really the key drivers of ageing and life span?
Current thinking in life‐history theory and the biology of ageing suggests that ageing rates,
and consequently life spans, evolve largely as a function of trade‐offs with reproduction …
and consequently life spans, evolve largely as a function of trade‐offs with reproduction …
Trade-offs (and constraints) in organismal biology
T Garland Jr, CJ Downs… - … and biochemical zoology, 2022 - journals.uchicago.edu
Trade-offs and constraints are inherent to life, and studies of these phenomena play a
central role in both organismal and evolutionary biology. Trade-offs can be defined …
central role in both organismal and evolutionary biology. Trade-offs can be defined …
Integrating theoretical and empirical approaches for a robust understanding of endocrine flexibility
JL Grindstaff, LE Beaty, M Ambardar… - Journal of …, 2022 - journals.biologists.com
There is growing interest in studying hormones beyond single 'snapshot'measurements, as
recognition that individual variation in the endocrine response to environmental change may …
recognition that individual variation in the endocrine response to environmental change may …
Trade-offs, pleiotropy, and shared molecular pathways: a unified view of constraints on adaptation
AA Mauro, CK Ghalambor - Integrative and Comparative Biology, 2020 - academic.oup.com
The concept of trade-offs permeates our thinking about adaptive evolution because they are
exhibited at every level of biological organization, from molecular and cellular processes to …
exhibited at every level of biological organization, from molecular and cellular processes to …
Hormonal pleiotropy structures genetic covariance
Quantitative genetic theory proposes that phenotypic evolution is shaped by G, the matrix of
genetic variances and covariances among traits. In species with separate sexes, the …
genetic variances and covariances among traits. In species with separate sexes, the …
Sex steroids as mediators of phenotypic integration, genetic correlations, and evolutionary transitions
RM Cox - Molecular and cellular endocrinology, 2020 - Elsevier
In recent decades, endocrinologists have increasingly adopted evolutionary methods and
perspectives to characterize the evolution of the vertebrate endocrine system and leverage it …
perspectives to characterize the evolution of the vertebrate endocrine system and leverage it …
Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells
Dengue virus (DENV) cycles between mosquito and mammalian hosts. To examine how
DENV populations adapt to these different host environments, we used serial passage in …
DENV populations adapt to these different host environments, we used serial passage in …
Evolution of hormone-phenotype couplings and hormone-genome interactions
When selection favors a new relationship between a cue and a hormonally mediated
response, adaptation can proceed by altering the hormonal signal that is produced or by …
response, adaptation can proceed by altering the hormonal signal that is produced or by …
The Danaid theory of aging
MJ Wensink, AA Cohen - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The classical evolutionary theories of aging suggest that aging evolves due to insufficient
selective pressure against it. In these theories, declining selection pressure with age leads …
selective pressure against it. In these theories, declining selection pressure with age leads …
Trade-off shapes diversity in eco-evolutionary dynamics
F Farahpour, M Saeedghalati, VS Brauer, D Hoffmann - elife, 2018 - elifesciences.org
We introduce an Interaction-and Trade-off-based Eco-Evolutionary Model (ITEEM), in which
species are competing in a well-mixed system, and their evolution in interaction trait space is …
species are competing in a well-mixed system, and their evolution in interaction trait space is …