Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics

A Chamoli, AS Gosavi, UP Shirwadkar, KV Wangdale… - Oral oncology, 2021 - Elsevier
Oral cavity squamous cell carcinoma (OCSCC) is the most common malignancy of the oral
cavity. The substantial risk factors for OCSCC are the consumption of tobacco products …

Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions

T Walsh, R Macey, AR Kerr, MW Lingen… - Cochrane Database …, 2021 - cochranelibrary.com
Background Squamous cell carcinoma is the most common form of malignancy of the oral
cavity, and is often proceeded by oral potentially malignant disorders (OPMD). Early …

A novel lightweight deep convolutional neural network for early detection of oral cancer

F Jubair, O Al‐karadsheh, D Malamos… - Oral …, 2022 - Wiley Online Library
Objectives To develop a lightweight deep convolutional neural network (CNN) for binary
classification of oral lesions into benign and malignant or potentially malignant using …

The emerging role of oral microbiota in oral cancer initiation, progression and stemness

PJ Saikia, L Pathak, S Mitra, B Das - Frontiers in Immunology, 2023 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is the most prevalent malignancy among the Head
and Neck cancer. OSCCs are highly inflammatory, immune-suppressive, and aggressive …

The use of salivary levels of matrix metalloproteinases as an adjuvant method in the early diagnosis of oral squamous cell carcinoma: a narrative literature review

M Monea, AM Pop - Current Issues in Molecular Biology, 2022 - mdpi.com
Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with increased
mortality, in which the early diagnosis is the most important step in increasing patients' …

Liquid biopsy and circulating biomarkers for the diagnosis of precancerous and cancerous oral lesions

G Gattuso, S Crimi, A Lavoro, R Rizzo, G Musumarra… - Non-coding RNA, 2022 - mdpi.com
Oral cancer is one of the most common malignancies worldwide, accounting for 2% of all
cases annually and 1.8% of all cancer deaths. To date, tissue biopsy and histopathological …

Identification of metabolism-associated biomarkers for early and precise diagnosis of oral squamous cell carcinoma

Y Wang, X Zhang, S Wang, Z Li, X Hu, X Yang, Y Song… - Biomolecules, 2022 - mdpi.com
The 5-year survival rate for oral squamous cell carcinoma (OSCC), one of the most common
head and neck cancers, has not improved in the last 20 years. Poor prognosis of OSCC is …

Diagnostic and therapeutic role of microRNAs in oral cancer

J Wang, N Lv, X Lu, R Yuan, Z Chen… - Oncology …, 2021 - spandidos-publications.com
Oral cancer is one of the leading types of cancer and remains the most common cause of
cancer‑related mortality in Asia. The pathogenesis of oral cancer is complicated and, due to …

PTP4A1 promotes oral squamous cell carcinoma (OSCC) metastasis through altered mitochondrial metabolic reprogramming

B Liu, W Si, B Wei, X Zhang, P Chen - Cell Death Discovery, 2023 - nature.com
PTP4A1 (Protein tyrosine phosphatase 4A1) is a protein tyrosine phosphatase that regulates
a range of pro-oncogenic signaling pathways. Here, we report a novel role for PTP4A1 in …

Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults

T Walsh, S Warnakulasuriya… - Cochrane Database …, 2021 - cochranelibrary.com
Background The early detection of oral cavity squamous cell carcinoma (OSCC) and oral
potentially malignant disorders (OPMD), followed by appropriate treatment, may improve …