Butyrate in energy metabolism: there is still more to learn

L Zhang, C Liu, Q Jiang, Y Yin - Trends in Endocrinology & Metabolism, 2021 - cell.com
Butyrate, a main product of gut microbial fermentation, has been recognized as an important
mediator of gut microbiota regulation in whole body energy homeostasis. However, the …

Dietary fiber‐derived short‐chain fatty acids: A potential therapeutic target to alleviate obesity‐related nonalcoholic fatty liver disease

S Zhang, J Zhao, F Xie, H He, LJ Johnston… - Obesity …, 2021 - Wiley Online Library
Over the past several decades, increasing global prevalence of obesity‐related
nonalcoholic fatty liver disease (NAFLD) has been one of main challenges to human health …

Butyrate to combat obesity and obesity‐associated metabolic disorders: Current status and future implications for therapeutic use

T van Deuren, EE Blaak, EE Canfora - Obesity Reviews, 2022 - Wiley Online Library
Evidence is increasing that disturbances in the gut microbiome may play a significant role in
the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …

[HTML][HTML] Role of butyrate, a gut microbiota derived metabolite, in cardiovascular diseases: A comprehensive narrative review

P Amiri, SA Hosseini, S Ghaffari, H Tutunchi… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) are major causes of death worldwide. Recently, new roles
for intestinal microbiota in pathology and treatment of CVD have been proposed. Butyrate, a …

Short-chain fatty acid, acylation and cardiovascular diseases

XF Chen, X Chen, X Tang - Clinical Science, 2020 - portlandpress.com
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.
Metabolic dysfunction is a fundamental core mechanism underlying CVDs. Previous studies …

The role of short-chain fatty acids of gut microbiota origin in hypertension

Y Wu, H Xu, X Tu, Z Gao - Frontiers in Microbiology, 2021 - frontiersin.org
Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases,
and its development involves multiple mechanisms. Gut microbiota has been reported to be …

Protective role of butyrate in obesity and diabetes: New insights

A Mayorga-Ramos, C Barba-Ostria… - Frontiers in …, 2022 - frontiersin.org
Studies in human microbiota dysbiosis have shown that short-chain fatty acids (SCFAs) like
propionate, acetate, and particularly butyrate, positively affect energy homeostasis …

The role of short-chain fatty acids in inflammatory skin diseases

X Xiao, X Hu, J Yao, W Cao, Z Zou, L Wang… - Frontiers in …, 2023 - frontiersin.org
Short-chain fatty acids (SCFAs) are metabolites of gut microbes that can modulate the host
inflammatory response, and contribute to health and homeostasis. Since the introduction of …

Butyrate generated by gut microbiota and its therapeutic role in metabolic syndrome

SC Bridgeman, W Northrop, PE Melton… - Pharmacological …, 2020 - Elsevier
Metabolic syndrome (MetS) and the associated incidence of cardiovascular disease and
type 2 diabetes represents a significant contributor to morbidity and mortality worldwide …

Diet-related changes of short-chain fatty acids in blood and feces in obesity and metabolic syndrome

T Ilyés, CN Silaghi, AM Crăciun - Biology, 2022 - mdpi.com
Simple Summary Short-chain fatty acids are produced by the bacteria present in the large
intestine. They are digestion products of fiber-containing foods and have many effects. Short …