Human genetic susceptibility to infectious disease
SJ Chapman, AVS Hill - Nature Reviews Genetics, 2012 - nature.com
Recent genome-wide studies have reported novel associations between common
polymorphisms and susceptibility to many major infectious diseases in humans. In parallel …
polymorphisms and susceptibility to many major infectious diseases in humans. In parallel …
[HTML][HTML] Functions of NOD-like receptors in human diseases
Y Zhong, A Kinio, M Saleh - Frontiers in immunology, 2013 - frontiersin.org
Nucleotide-binding and oligomerization domain NOD-like receptors (NLRs) are highly
conserved cytosolic pattern recognition receptors that perform critical functions in surveying …
conserved cytosolic pattern recognition receptors that perform critical functions in surveying …
Leprosy in the 21st century
C White, C Franco-Paredes - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Despite significant improvements in leprosy (Hansen's disease) treatment and outlook for
patients since the introduction of multidrug therapy (MDT) 3 decades ago, the global …
patients since the introduction of multidrug therapy (MDT) 3 decades ago, the global …
[HTML][HTML] Regulation of the antimicrobial response by NLR proteins
Nucleotide-binding, oligomerization domain (NOD)-like receptor (NLR) proteins are a family
of innate immune receptors that play a pivotal role in microbial sensing, leading to the …
of innate immune receptors that play a pivotal role in microbial sensing, leading to the …
[HTML][HTML] NOD1 and NOD2 signaling in infection and inflammation
LO Moreira, DS Zamboni - Frontiers in immunology, 2012 - frontiersin.org
Sensing intracellular pathogens is a process mediated by innate immune cells that is crucial
for the induction of inflammatory processes and effective adaptive immune responses …
for the induction of inflammatory processes and effective adaptive immune responses …
[HTML][HTML] The NLR family of innate immune and cell death sensors
B Sundaram, RE Tweedell, SP Kumar, TD Kanneganti - Immunity, 2024 - cell.com
Nucleotide-binding oligomerization domain (NOD)-like receptors, also known as nucleotide-
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …
Leprosy: an overview of pathophysiology
RM Bhat, C Prakash - Interdisciplinary perspectives on …, 2012 - Wiley Online Library
Leprosy, also known as Hansen's disease, is a chronic infectious disease caused by
Mycobacterium leprae, a microorganism that has a predilection for the skin and nerves. The …
Mycobacterium leprae, a microorganism that has a predilection for the skin and nerves. The …
[HTML][HTML] Advances in the immunology and genetics of leprosy
Z Mi, H Liu, F Zhang - Frontiers in immunology, 2020 - frontiersin.org
Leprosy, a disease caused by the intracellular parasite Mycobacterium leprae or
Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a …
Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a …
[HTML][HTML] A systematic review of immunological studies of erythema nodosum leprosum
A Polycarpou, SL Walker, DNJ Lockwood - Frontiers in immunology, 2017 - frontiersin.org
Erythema nodosum leprosum (ENL) is a painful inflammatory complication of leprosy
occurring in 50% of lepromatous leprosy patients and 5–10% of borderline lepromatous …
occurring in 50% of lepromatous leprosy patients and 5–10% of borderline lepromatous …
Receptor‐mediated recognition of mycobacterial pathogens
KE Killick, C Ní Cheallaigh, C O'Farrelly… - Cellular …, 2013 - Wiley Online Library
Mycobacteria are a genus of bacteria that range from the non‐pathogenic M ycobacterium
smegmatis to M ycobacterium tuberculosis, the causative agent of tuberculosis in humans …
smegmatis to M ycobacterium tuberculosis, the causative agent of tuberculosis in humans …