Summary CD26/DPP4 (dipeptidyl peptidase 4/DP4/DPPIV) is a surface T cell activation
antigen and has been shown to have DPP4 enzymatic activity, cleaving-off amino-terminal …

The enteric nervous system (ENS), referred to as the “second brain,” comprises a vast
number of neurons that form an elegant network throughout the gastrointestinal tract …

The Dipeptidyl peptidase-4 (DPP-4) activity influences metabolic, behavioral and intestinal
disorders through the cleavage of key hormones and peptides. Some studies describe the …

Ulcerative colitis (UC) is a chronic inflammatory disease with increasing incidence and
prevalence worldwide. Currently used treatments of UC are unsatisfactory, while natural …

Objectives: Farnesoid X receptor (FXR) activation is involved in ameliorating inflammatory
bowel disease (IBD), such as ulcerative colitis (UC), and inflammatory regulation may be …

The inflammatory bowel diseases (IBDs), including Crohn's disease (CD) and ulcerative
colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract and involve a …

Background Given the rising prevalence of diabetes mellitus (DM) and the limited data on its
effect on the course of inflammatory bowel disease (IBD), we characterized multiyear …

Intestinal epithelial cells constantly crosstalk with the gut microbiota and immune cells of the
gut lamina propria. Enteroendocrine cells, secrete hormones, such as incretin hormones …

Abstract Dipeptidyl peptidase IV (DPP IV/CD26) is a widely distributed multifunctional
protein that plays a significant role in different physiological as well as pathological …

Abstract Dipeptidyl peptidase 4 (DPP-4) is a serine protease, which has enzymatic activity to
selectively clean the N-terminal dipeptide of peptides and proteins with proline or alanine in …