Nicotine is the key addictive constituent of tobacco. It is not a carcinogen, but it drives
smoking and the continued exposure to the many carcinogens present in tobacco. The …

Lung cancer continues to be a significant burden worldwide and remains the leading cause
of cancer-associated mortality. Two considerable challenges posed by this disease are the …

Background: Cotinine is a metabolite of nicotine. Serum and urinary cotinine are validated
biomarkers for cigarette exposure. Their performance for lung cancer risk prediction has not …

Background: While cigarette smoking is the leading cause of lung cancer, the majority of
smokers do not develop the disease over their lifetime. The inter-individual differences in …

Background The aetiology of lung cancer among individuals who never smoked remains
elusive, despite 15% of lung cancer cases in men and 53% in women worldwide being …

Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary
non-pathologically across population groups. We described variation in concentrations of …

The association between tobacco smoke exposure and sleep has been widely discussed,
but the correlation between serum cotinine levels and sleep health outcomes in adolescents …

Associations of coffee and tea consumption with lung cancer risk have been inconsistent,
and most lung cancer cases investigated were smokers. Included in this study were over 1.1 …

Background A better understanding of lung cancer etiology and the development of
screening biomarkers have important implications for lung cancer prevention. Methods We …

Background Lung cancer (LC) is the leading cause of cancer-related deaths in the United
States (US), with non-White people who smoke often bearing the burden of the highest rate …