Since the discovery of L-thyroxine, the main secretory product of the thyroid gland, and its
major metabolite T3, which exerts the majority of thyroid hormone action via ligand …

The rediscovery of the group of thyronamines (TAMs), especially the first detailed description
of their most prominent congener 3-iodothyronamine (3T1AM) 14 years ago, boosted …

Background: A novel form of thyroid hormone (TH) signaling is represented by 3-
iodothyronamine (T1AM), an endogenous TH derivative that interacts with specific molecular …

Background: 3-Iodothyroacetic acid (TA1) is among the thyroid hormone (T3) metabolites
that can acutely modify behavior in mice. This study aimed to investigate whether TA1 is also …

Abstract The 3-iodothyronamine (T1AM) and 3-iodothryoacetic acid (TA1), are endogenous
occurring compounds structurally related with thyroid hormones (THs, the pro-hormone T4 …

3-Iodothyronamine (T1AM) is the last iodinated thyronamine generated from thyroid
hormone alternative metabolism found circulating in rodents and in humans. So far, the …

3-iodothyroacetic acid (TA1), an end metabolite of thyroid hormone, has been shown to
produce behavioral effects in mice that are dependent on brain histamine. We now aim to …

Synthetic thyroid hormones, particularly levothyroxine, are a concern in horse racing due to
their performance-enhancing effects. Regulating these substances is essential to prevent …

Triple-negative breast cancer (TNBC) is a highly aggressive cancer subtype with poor
patient survival due to high rates of metastasis and a lack of targeted treatments. Recently, a …