One of the leading causes of death worldwide, in both men and women, is cancer. Despite
the significant development in therapeutic strategies, the inevitable emergence of drug …

Recent evidence suggests that autophagy is a governed catabolic framework enabling the
recycling of nutrients from injured organelles and other cellular constituents via a lysosomal …

In photodynamic therapy (PDT), elevated reactive oxygen species (ROS) activate tumor cell
protective autophagy, therefore attenuating the antitumor function of therapy. Hence …

Long noncoding RNAs (lncRNAs) are a subclass of noncoding RNAs composed of more
than 200 nucleotides without the ability to encode functional proteins. Given their …

Endometrial cancer is the most common gynecologic cancer and one of the only cancers for
which incidence and mortality is steadily increasing. Although curable with surgery in the …

Paclitaxel, a natural anticancer drug, is widely recognized and extensively utilized in the
treatment of breast cancer (BC). However, it may lead to certain side effects or drug …

Up till the present moment, breast cancer is still the leading cause of cancer-related death in
women worldwide. Although the treatment methods and protocols for breast cancer are …

Autophagy is a critical cellular adaptive response in tumor formation. Nutritional deficiency
and hypoxia exacerbate autophagic flux in established malignancies, promoting tumor cell …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with progressive
loss of motor neurons in the spinal cord, cerebral cortex and brain stem. ALS is …

This study aimed to explore the efficacy and potential mechanisms of rechallenge therapy
with microtubule-targeting agents (MTAs) in patients with HER2-low metastatic breast …