A comprehensive review on tyrosinase inhibitors

S Zolghadri, A Bahrami, MT Hassan Khan… - Journal of enzyme …, 2019 - Taylor & Francis
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …

Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: A systematic review

RJ Obaid, EU Mughal, N Naeem, A Sadiq… - RSC …, 2021 - pubs.rsc.org
Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

Recent advances in the design and discovery of synthetic tyrosinase inhibitors

J Li, L Feng, L Liu, F Wang, L Ouyang, L Zhang… - European Journal of …, 2021 - Elsevier
Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …

Natural and bioinspired phenolic compounds as tyrosinase inhibitors for the treatment of skin hyperpigmentation: Recent advances

L Panzella, A Napolitano - Cosmetics, 2019 - mdpi.com
One of the most common approaches for control of skin pigmentation involves the inhibition
of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis …

Tyrosinase inhibitors naturally present in plants and synthetic modifications of these natural products as anti-melanogenic agents: a review

M Hassan, S Shahzadi, A Kloczkowski - Molecules, 2023 - mdpi.com
Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …

Tyrosinase inhibitors from natural and synthetic sources as skin-lightening agents

MN Masum, K Yamauchi, T Mitsunaga - Reviews in Agricultural …, 2019 - jstage.jst.go.jp
Melanin, a major pigment in mammalian skin, is known to protect the skin against harmful
effects of ultraviolet (UV) irradiation, oxidative stress, and DNA damage. The accumulation …

Tyrosinase inhibitors as potential antibacterial agents

Y Yuan, W Jin, Y Nazir, C Fercher… - European Journal of …, 2020 - Elsevier
Tyrosinase is a copper-containing enzyme that catalyzes the biosynthesis of melanin. This
enzyme is present in bacteria, fungi, plants and animals, and plays multiple roles in …

Green synthesis of biogenic zinc oxide nanoflower as dual agent for photodegradation of an organic dye and tyrosinase inhibitor

AC Ekennia, DN Uduagwu, NN Nwaji, OO Oje… - Journal of Inorganic and …, 2021 - Springer
In the study, metabolites of Euphorbia sanguinea were used as benign reducing and
stabilizing agents to obtain zinc oxide nanoparticles (ZnO-NPs). The nanoparticles were …

Biosynthesis of zinc oxide nanoparticles using leaf extracts of Alchornea laxiflora and its tyrosinase inhibition and catalytic studies

A Ekennia, D Uduagwu, O Olowu, O Nwanji, O Oje… - Micron, 2021 - Elsevier
Abstract Zinc oxide nanoparticles (ZnO-NPs) were synthesized using a simple, low cost and
safe method involving aqueous leaf extracts of Alchornea laxiflora and a zinc precursor salt …

Naturally-occurring tyrosinase inhibitors classified by enzyme kinetics and copper chelation

HD Kim, H Choi, F Abekura, JY Park, WS Yang… - International Journal of …, 2023 - mdpi.com
Currently, there are three major assaying methods used to validate in vitro whitening activity
from natural products: methods using mushroom tyrosinase, human tyrosinase, and …