Follicular Helper CD4 T Cells (TFH)
S Crotty - Annual review of immunology, 2011 - annualreviews.org
T cell help to B cells is a fundamental aspect of adaptive immunity and the generation of
immunological memory. Follicular helper CD4 T (TFH) cells are the specialized providers of …
immunological memory. Follicular helper CD4 T (TFH) cells are the specialized providers of …
[PDF][PDF] Cell culture media: a review
M Arora - Mater methods, 2013 - researchgate.net
Types of Cell Culture Media Animal cells can be cultured either using a completely natural
medium or an artificial/synthetic medium along with some natural products. Natural Media …
medium or an artificial/synthetic medium along with some natural products. Natural Media …
Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas
GD Victora, D Dominguez-Sola… - Blood, The Journal …, 2012 - ashpublications.org
Germinal centers (GCs) are sites of B-cell clonal expansion, hypermutation, and selection.
GCs are polarized into dark (DZ) and light zones (LZ), a distinction that is of key importance …
GCs are polarized into dark (DZ) and light zones (LZ), a distinction that is of key importance …
Human memory B cells originate from three distinct germinal center-dependent and-independent maturation pathways
MA Berkowska, GJA Driessen, V Bikos… - Blood, The Journal …, 2011 - ashpublications.org
Multiple distinct memory B-cell subsets have been identified in humans, but it remains
unclear how their phenotypic diversity corresponds to the type of responses from which they …
unclear how their phenotypic diversity corresponds to the type of responses from which they …
Mechanisms of B cell autoimmunity in SLE
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is known to be
associated with polyclonal B-cell hyperreactivity. The underlying causes of the diffuse B-cell …
associated with polyclonal B-cell hyperreactivity. The underlying causes of the diffuse B-cell …
The memory B cell response to influenza vaccination is impaired in older persons
AR Burton, SM Guillaume, WS Foster, AK Wheatley… - Cell reports, 2022 - cell.com
Influenza infection imparts an age-related increase in mortality and morbidity. The most
effective countermeasure is vaccination; however, vaccines offer modest protection in older …
effective countermeasure is vaccination; however, vaccines offer modest protection in older …
B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1
K Kwak, H Sohn, R George, C Torgbor… - Science …, 2023 - science.org
The demand for a vaccine for coronavirus disease 2019 (COVID-19) highlighted gaps in our
understanding of the requirements for B cell responses to antigens, particularly to …
understanding of the requirements for B cell responses to antigens, particularly to …
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune …
X Xiao, W Chen, Y Feng, Z Zhu, P Prabakaran… - Biochemical and …, 2009 - Elsevier
Several human monoclonal antibodies (hmAbs) including b12, 2G12, and 2F5 exhibit
relatively potent and broad HIV-1-neutralizing activity. However, their elicitation in vivo by …
relatively potent and broad HIV-1-neutralizing activity. However, their elicitation in vivo by …
The interplay between CD27dull and CD27bright B cells ensures the flexibility, stability, and resilience of human B cell memory
Memory B cells (MBCs) epitomize the adaptation of the immune system to the environment.
We identify two MBC subsets in peripheral blood, CD27 dull and CD27 bright MBCs, whose …
We identify two MBC subsets in peripheral blood, CD27 dull and CD27 bright MBCs, whose …
Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue
Human memory B cells and marginal zone (MZ) B cells share common features such as the
expression of CD27 and somatic mutations in their IGHV and BCL6 genes, but the …
expression of CD27 and somatic mutations in their IGHV and BCL6 genes, but the …