Host–parasite co-evolution and its genomic signature

D Ebert, PD Fields - Nature Reviews Genetics, 2020 - nature.com
Studies in diverse biological systems have indicated that host–parasite co-evolution is
responsible for the extraordinary genetic diversity seen in some genomic regions, such as …

[HTML][HTML] Advances in the evolutionary understanding of MHC polymorphism

J Radwan, W Babik, J Kaufman, TL Lenz, J Winternitz - Trends in Genetics, 2020 - cell.com
Proteins encoded by the classical major histocompatibility complex (MHC) genes incite the
vertebrate adaptive immune response by presenting peptide antigens on the cell surface …

The inflated significance of neutral genetic diversity in conservation genetics

JC Teixeira, CD Huber - Proceedings of the National …, 2021 - National Acad Sciences
The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …

[图书][B] Evolutionary parasitology: the integrated study of infections, immunology, ecology, and genetics

P Schmid-Hempel - 2021 - books.google.com
Parasites and infectious diseases are everywhere and represent some of the most potent
forces shaping the natural world. They affect almost every aspect imaginable in the life of …

Long-term balancing selection for pathogen resistance maintains trans-species polymorphisms in a planktonic crustacean

L Cornetti, PD Fields, L Du Pasquier, D Ebert - Nature Communications, 2024 - nature.com
Balancing selection is an evolutionary process that maintains genetic polymorphisms at
selected loci and strongly reduces the likelihood of allele fixation. When allelic …

Threespine stickleback: A model system for evolutionary genomics

K Reid, MA Bell, KR Veeramah - Annual review of genomics …, 2021 - annualreviews.org
The repeated adaptation of oceanic threespine sticklebacks to fresh water has made it a
premier organism to study parallel evolution. These small fish have multiple distinct …

Major H istocompatibility C omplex class II b polymorphism influences gut microbiota composition and diversity

DI Bolnick, LK Snowberg, JG Caporaso… - Molecular …, 2014 - Wiley Online Library
Animals harbour diverse communities of symbiotic bacteria, which differ dramatically among
host individuals. This heterogeneity poses an immunological challenge: distinguishing …

Adaptive tolerance to a pathogenic fungus drives major histocompatibility complex evolution in natural amphibian populations

AE Savage, KR Zamudio - Proceedings of the Royal …, 2016 - royalsocietypublishing.org
Amphibians have been affected globally by the disease chytridiomycosis, caused by the
fungus Batrachochytrium dendrobatidis (Bd), and we are just now beginning to understand …

Patterns of MHC‐dependent mate selection in humans and nonhuman primates: a meta‐analysis

J Winternitz, JL Abbate, E Huchard… - Molecular …, 2017 - Wiley Online Library
Genes of the major histocompatibility complex (MHC) in vertebrates are integral for effective
adaptive immune response and are associated with sexual selection. Evidence from a range …

Rapid trait evolution drives increased speed and variance in experimental range expansions

C Weiss-Lehman, RA Hufbauer… - Nature communications, 2017 - nature.com
Range expansions are central to two ecological issues reshaping patterns of global
biodiversity: biological invasions and climate change. Traditional theory considers range …