Leishmaniasis and Chagas disease chemotherapy: a critical review
I Silva-Jardim, OH Thiemann, FF Anibal - Journal of the Brazilian …, 2014 - SciELO Brasil
Leishmaniasis and Chagas disease, caused by the kinetoplastid parasites Leishmania spp
and Trypanosoma cruzi, respectively, are among the most important parasitic diseases …
and Trypanosoma cruzi, respectively, are among the most important parasitic diseases …
[HTML][HTML] Niosomal formulation of amphotericin B alone and in combination with glucantime: In vitro and in vivo leishmanicidal effects
This study aimed to evaluate the efficacy of glucantime and amphotericin B (AmB)
encapsulated in niosome against cutaneous leishmaniasis (CL) using in vitro and in vivo …
encapsulated in niosome against cutaneous leishmaniasis (CL) using in vitro and in vivo …
Meglumine antimoniate is more effective than sodium stibogluconate in the treatment of cutaneous leishmaniasis
Sodium stibogluconate (SSG, Pentostam) and meglumine antimoniate (MA, Glucantime) are
two antimonials that are widely used to treat cutaneous leishmaniasis (CL), but the relative …
two antimonials that are widely used to treat cutaneous leishmaniasis (CL), but the relative …
Leishmanicidal effects of amphotericin B in combination with selenium loaded on niosome against Leishmania tropica
The strategy for improving the treatment of leishmaniasis by the World Health Organization,
is the development of new drugs and combination therapy. The aim of this survey was to …
is the development of new drugs and combination therapy. The aim of this survey was to …
Leishmaniasis: history, evolution of treatment and the need for new drugs
E Azevedo Cardoso, A Rodrigues da Silva… - Current …, 2014 - ingentaconnect.com
Leishmaniasis is defined as a cluster of infectious diseases caused by protozoan parasites
of the genus Leishmania. It is recognized worldwide as a major health problem, showing …
of the genus Leishmania. It is recognized worldwide as a major health problem, showing …
[HTML][HTML] A novel niosomal combination of selenium coupled with glucantime against Leishmania tropica
There is no effective treatment modality available against different forms of leishmaniasis.
Therefore, the aim of this study was to improve the penetration and efficacy of selenium and …
Therefore, the aim of this study was to improve the penetration and efficacy of selenium and …
Ursolic acid potentializes conventional therapy in experimental leishmaniasis
JA Jesus, TN Fragoso da Silva, ES Yamamoto… - Pathogens, 2020 - mdpi.com
Ursolic acid (UA) is a triterpene with a broad array of pharmacological activities. In
leishmaniasis, UA killed different species of parasites, and it was active in the experimental …
leishmaniasis, UA killed different species of parasites, and it was active in the experimental …
The Effects of Polyhexamethylene Biguanide (PHMB) and TLR Agonists Alone or as Polyplex Nanoparticles against Leishmania infantum Promastigotes and …
P Martínez-Orellana, M Baxarias, L Good… - Veterinary …, 2020 - mdpi.com
Dogs are the main reservoir for Leishmania infantum, manifesting from a subclinical to a
fatal disease. Limited treatments are available, although new antiparasitics and …
fatal disease. Limited treatments are available, although new antiparasitics and …
Overcoming the Challenge; In Vivo Efficacy of Miltefosine for Chronic Cutaneous Leishmaniasis
Abstract Background Cutaneous Leishmaniasis (CL) is the most common form of
leishmaniasis. CL can be divided into two major groups: acute CL (ACL) and chronic CL …
leishmaniasis. CL can be divided into two major groups: acute CL (ACL) and chronic CL …
[HTML][HTML] A novel strategy for enhance potentiation of meglumine antimoniate against Leishmania major in vitro
F Mirzaei, H Khanahmad, F Namdar… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Background: We aimed to design a different method of drug delivery for increased transfer of
the choice drug (meglumine antimoniate) within the host cells. Therefore, listeriolysin O …
the choice drug (meglumine antimoniate) within the host cells. Therefore, listeriolysin O …