Importance Multiple myeloma is a hematologic malignancy characterized by presence of
abnormal clonal plasma cells in the bone marrow, with potential for uncontrolled growth …

Bone metastasis is a major cause of morbidity in persons with cancer. Complications include
pain, impaired mobility, pathological fracture, spinal cord compression, cranial nerve …

There are three distinct areas of cancer management that make bone health in cancer
patients of increasing clinical importance. First, bone metastases are common in many solid …

Abstract The European Myeloma Network provides recommendations for the management
of the most common complications of multiple myeloma. Whole body low-dose computed …

Robust establishment of survival in multiple myeloma (MM) and its relationship to recurrent
genetic aberrations is required as outcomes are variable despite apparent similar staging …

Purpose The aim of the International Myeloma Working Group was to develop practice
recommendations for the management of multiple myeloma (MM)–related bone disease …

Purpose To provide an update on recent advances in the management of patients with
multiple myeloma who are not eligible for autologous stem-cell transplantation. Methods A …

Several haematological malignancies, including multiple myeloma (MM) and acute myeloid
leukaemia (AML), have well-defined precursor states that precede the development of overt …

Multiple myeloma (MM) is a plasma cell cancer that develops in the skeleton causing
profound bone destruction and fractures. The bone disease is mediated by increased …

Bone disease is a cardinal complication of multiple myeloma that affects quality of life and
survival. Osteocytes have emerged as key players in the development of myeloma-related …